Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE011303-03
Application #
2132543
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1994-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Texas A&M University
Department
Veterinary Sciences
Type
Schools of Veterinary Medicine
DUNS #
047006379
City
College Station
State
TX
Country
United States
Zip Code
77845
Gefrides, Lisa A; Bennett, Gregory D; Finnell, Richard H (2002) Effects of folate supplementation on the risk of spontaneous and induced neural tube defects in Splotch mice. Teratology 65:63-9
Finnell, R H; Gelineau-van Waes, J; Bennett, G D et al. (2000) Genetic basis of susceptibility to environmentally induced neural tube defects. Ann N Y Acad Sci 919:261-77
Craig, J C; Bennett, G D; Miranda, R C et al. (2000) Ribonucleotide reductase subunit R1: a gene conferring sensitivity to valproic acid-induced neural tube defects in mice. Teratology 61:305-13
McAlhany Jr, R E; Miranda, R C; Finnell, R H et al. (1999) Ethanol decreases Glial-Derived Neurotrophic Factor (GDNF) protein release but not mRNA expression and increases GDNF-stimulated Shc phosphorylation in the developing cerebellum. Alcohol Clin Exp Res 23:1691-7
Finnell, R H; Bennett, G D; Mather, G G et al. (1999) Effect of stiripentol dose on phenytoin-induced teratogenesis in a mouse model. Reprod Toxicol 13:85-91
Gelineau-van Waes, J; Bennett, G D; Finnell, R H (1999) Phenytoin-induced alterations in craniofacial gene expression. Teratology 59:23-34
Finnell, R H; Greer, K A; Barber, R C et al. (1998) Neural tube and craniofacial defects with special emphasis on folate pathway genes. Crit Rev Oral Biol Med 9:38-53
Bennett, G D; An, J; Craig, J C et al. (1998) Neurulation abnormalities secondary to altered gene expression in neural tube defect susceptible Splotch embryos. Teratology 57:17-29
Finnell, R H; Wlodarczyk, B C; Craig, J C et al. (1997) Strain-dependent alterations in the expression of folate pathway genes following teratogenic exposure to valproic acid in a mouse model. Am J Med Genet 70:303-11
Craig, J C; Eberwine, J H; Calvin, J A et al. (1997) Developmental expression of morphoregulatory genes in the mouse embryo: an analytical approach using a novel technology. Biochem Mol Med 60:81-91

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