Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE011368-03
Application #
2132645
Study Section
Special Emphasis Panel (ZDE1-YS (33))
Project Start
1994-09-30
Project End
1998-09-29
Budget Start
1996-09-30
Budget End
1998-09-29
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Health Science Center San Antonio
Department
Dentistry
Type
Schools of Dentistry
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Holt, Stanley C; Ebersole, Jeffrey L (2005) Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia: the ""red complex"", a prototype polybacterial pathogenic consortium in periodontitis. Periodontol 2000 38:72-122
Kesavalu, L; Holt, S C; Ebersole, J L (2003) In vitro environmental regulation of Porphyromonas gingivalis growth and virulence. Oral Microbiol Immunol 18:226-33
Kesavalu, L; Chandrasekar, B; Ebersole, J L (2002) In vivo induction of proinflammatory cytokines in mouse tissue by Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans. Oral Microbiol Immunol 17:177-80
Kesavalu, Lakshmyya; Falk, Clinton W; Davis, Kenneth J et al. (2002) Biological characterization of lipopolysaccharide from Treponema pectinovorum. Infect Immun 70:211-7
Xu, Xiaoping; Kolodrubetz, David (2002) Construction and analysis of hemin binding protein mutants in the oral pathogen Treponema denticola. Res Microbiol 153:569-77
Xu, X; Holt, S C; Kolodrubetz, D (2001) Cloning and expression of two novel hemin binding protein genes from Treponema denticola. Infect Immun 69:4465-72
Nixon, C S; Steffen, M J; Ebersole, J L (2000) Cytokine responses to treponema pectinovorum and treponema denticola in human gingival fibroblasts. Infect Immun 68:5284-92
Chu, L; Ebersole, J L; Kurzban, G P et al. (1999) Cystalysin, a 46-kDa L-cysteine desulfhydrase from Treponema denticola: biochemical and biophysical characterization. Clin Infect Dis 28:442-50
Kurzban, G P; Chu, L; Ebersole, J L et al. (1999) Sulfhemoglobin formation in human erythrocytes by cystalysin, an L-cysteine desulfhydrase from Treponema denticola. Oral Microbiol Immunol 14:153-64
Kesavalu, L; Holt, S C; Ebersole, J L (1999) Environmental modulation of oral treponeme virulence in a murine model. Infect Immun 67:2783-9

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