Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE011423-07
Application #
2132736
Study Section
Drug Abuse Biomedical Research Review Committee (DABR)
Project Start
1990-06-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Chicago
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Hammond, D L (2001) J.J. Bonica Lecture--2001: role of spinal GABA in acute and persistent nociception. Reg Anesth Pain Med 26:551-7
Ugarte, S D; Homanics, G E; Hammond, D L (2001) Effect of embryonic knock-down of GABAA receptors on the levels of monoamines and their metabolites in the CNS of the mouse. Brain Res 904:290-7
Ugarte, S D; Homanics, G E; Firestone, L L et al. (2000) Sensory thresholds and the antinociceptive effects of GABA receptor agonists in mice lacking the beta3 subunit of the GABA(A) receptor. Neuroscience 95:795-806
John, J M; Kaneko, M; Hammond, D L (1998) Intrathecal bicuculline does not increase formalin-induced inflammation. Brain Res 794:320-4
Hammond, D L; Nelson, V; Thomas, D A (1998) Intrathecal methysergide antagonizes the antinociception, but not the hyperalgesia produced by microinjection of baclofen in the ventromedial medulla of the rat. Neurosci Lett 244:93-6
Hama, A T; Fritschy, J M; Hammond, D L (1997) Differential distribution of (GABA)A receptor subunits on bulbospinal serotonergic and nonserotonergic neurons of the ventromedial medulla of the rat. J Comp Neurol 384:337-48
Kaneko, M; Hammond, D L (1997) Role of spinal gamma-aminobutyric acidA receptors in formalin-induced nociception in the rat. J Pharmacol Exp Ther 282:928-38
Mason, P; Owens, C A; Hammond, D L (1996) Antagonism of the antinocifensive action of halothane by intrathecal administration of GABAA receptor antagonists. Anesthesiology 84:1205-14
Thomas, D A; Navarrete, I M; Graham, B A et al. (1996) Antinociception produced by systemic R(+)-baclofen hydrochloride is attenuated by CGP 35348 administered to the spinal cord or ventromedial medulla of rats. Brain Res 718:129-37
Thomas, D A; McGowan, M K; Hammond, D L (1995) Microinjection of baclofen in the ventromedial medulla of rats: antinociception at low doses and hyperalgesia at high doses. J Pharmacol Exp Ther 275:274-84