Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE014757-02
Application #
6711091
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Program Officer
Mangan, Dennis F
Project Start
2003-03-03
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$313,556
Indirect Cost
Name
University of California Los Angeles
Department
Dentistry
Type
Schools of Dentistry
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Merritt, J; Qi, F (2012) The mutacins of Streptococcus mutans: regulation and ecology. Mol Oral Microbiol 27:57-69
Hung, David C I; Downey, Jennifer S; Kreth, Jens et al. (2012) Oligomerization of the response regulator ComE from Streptococcus mutans is affected by phosphorylation. J Bacteriol 194:1127-35
Hung, David C I; Downey, Jennifer S; Ayala, Eduardo A et al. (2011) Characterization of DNA binding sites of the ComE response regulator from Streptococcus mutans. J Bacteriol 193:3642-52
Wu, Chenggang; Ayala, Eduardo A; Downey, Jennifer S et al. (2010) Regulation of ciaXRH operon expression and identification of the CiaR regulon in Streptococcus mutans. J Bacteriol 192:4669-79
Wu, Chenggang; Cichewicz, Robert; Li, Yihong et al. (2010) Genomic island TnSmu2 of Streptococcus mutans harbors a nonribosomal peptide synthetase-polyketide synthase gene cluster responsible for the biosynthesis of pigments involved in oxygen and H2O2 tolerance. Appl Environ Microbiol 76:5815-26
Okinaga, T; Xie, Z; Niu, G et al. (2010) Examination of the hdrRM regulon yields insight into the competence system of Streptococcus mutans. Mol Oral Microbiol 25:165-77
Niu, Guoqing; Okinaga, Toshinori; Qi, Fengxia et al. (2010) The Streptococcus mutans IrvR repressor is a CI-like regulator that functions through autocleavage and Clp-dependent proteolysis. J Bacteriol 192:1586-95
Xie, Zhoujie; Okinaga, Toshinori; Niu, Guoqing et al. (2010) Identification of a novel bacteriocin regulatory system in Streptococcus mutans. Mol Microbiol 78:1431-47
Okinaga, Toshinori; Niu, Guoqing; Xie, Zhoujie et al. (2010) The hdrRM operon of Streptococcus mutans encodes a novel regulatory system for coordinated competence development and bacteriocin production. J Bacteriol 192:1844-52
Kreth, Jens; Merritt, Justin; Qi, Fengxia (2009) Bacterial and host interactions of oral streptococci. DNA Cell Biol 28:397-403

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