Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK017389-24
Application #
2137077
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1977-08-01
Project End
1999-07-31
Budget Start
1996-08-22
Budget End
1997-07-31
Support Year
24
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Valentijn, J A; Valentijn, K; Pastore, L M et al. (2000) Actin coating of secretory granules during regulated exocytosis correlates with the release of rab3D. Proc Natl Acad Sci U S A 97:1091-5
Valentijn, K M; Gumkowski, F D; Jamieson, J D (1999) The subapical actin cytoskeleton regulates secretion and membrane retrieval in pancreatic acinar cells. J Cell Sci 112 ( Pt 1):81-96
Valentijn, J A; Jamieson, J D (1998) Carboxyl methylation of rab3D is developmentally regulated in the rat pancreas: correlation with exocrine function. Eur J Cell Biol 76:204-11
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Valentijn, J A; Sengupta, D; Gumkowski, F D et al. (1996) Rab3D localizes to secretory granules in rat pancreatic acinar cells. Eur J Cell Biol 70:33-41
Valentijn, J A; Gumkowski, F D; Jamieson, J D (1996) The expression pattern of rab3D in the developing rat exocrine pancreas coincides with the acquisition of regulated exocytosis. Eur J Cell Biol 71:129-36
Sengupta, D; Gumkowski, F D; Tang, L H et al. (1996) Localization of cellubrevin to the Golgi complex in pancreatic acinar cells. Eur J Cell Biol 70:306-14
O'Sullivan, A J; Jamieson, J D (1992) Activation of protein kinase C is not an absolute requirement for amylase release from permeabilized rat pancreatic acini. Biochem J 285 ( Pt 2):597-601
Jena, B P; Brennwald, P; Garrett, M D et al. (1992) Distinct and specific GAP activities in rat pancreas act on the yeast GTP-binding proteins Ypt1 and Sec4. FEBS Lett 309:5-9
Cher, D J; Padfield, P J; Jamieson, J D (1992) Amylase release from streptolysin O permeabilized fetal pancreatic acini. Am J Physiol 262:G719-26

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