Regulation of Expression of Lipogenic Genes

Goodridge, Alan Gardner

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 5R01DK021594-19
• Application #: 2137590
• Study Section: Physiological Chemistry Study Section (PC)
• Project Start: 1987-09-01
• Project End: 1997-08-31
• Budget Start: 1995-09-01
• Budget End: 1997-08-31
• Support Year: 19
• Fiscal Year: 1995

Institution

• Name: University of Iowa
• Department: Biochemistry
• Type: Schools of Medicine
• DUNS #: 041294109
• City: Iowa City
• State: IA
• Country: United States
• Zip Code: 52242

Publications

Chung, S S; Goodridge, A G (1999) Cis-acting elements in the 5'-flanking DNA of the malic enzyme gene regulate tissue-specific T3-responsiveness in chick embryo fibroblasts. Arch Biochem Biophys 364:1-12

Chung, S S; MacPhee, K G; Goodridge, A G (1999) Effect of the CCAAT/enhancer binding protein on expression of the gene for chicken malic enzyme. Arch Biochem Biophys 364:30-41

Xu, G; Goodridge, A G (1999) Function of a C-rich sequence in the polypyrimidine/polypurine tract of the promoter of the chicken malic enzyme gene depends on promoter context. Arch Biochem Biophys 363:202-12

Thurmond, D C; Baillie, R A; Goodridge, A G (1998) Regulation of the action of steroid/thyroid hormone receptors by medium-chain fatty acids. J Biol Chem 273:15373-81

Thurmond, D C; Goodridge, A G (1998) Characterization of thyroid hormone response elements in the gene for chicken malic enzyme. Factors that influence triiodothyronine responsiveness. J Biol Chem 273:1613-22

Xu, G; Goodridge, A G (1998) A CT repeat in the promoter of the chicken malic enzyme gene is essential for function at an alternative transcription start site. Arch Biochem Biophys 358:83-91

Mounier, C; Chen, W; Klautky, S A et al. (1997) Cyclic AMP-mediated inhibition of transcription of the malic enzyme gene in chick embryo hepatocytes in culture. Characterization of a cis-acting element far upstream of the promoter. J Biol Chem 272:23606-15

Carlisle, T L; Roncero, C; el Khadir-Mounier, C et al. (1996) Malic enzyme gene in chick embryo hepatocytes in culture: clofibrate regulates responsiveness to triiodothyronine. J Lipid Res 37:2088-97

Hodnett, D W; Fantozzi, D A; Thurmond, D C et al. (1996) The chicken malic enzyme gene: structural organization and identification of triiodothyronine response elements in the 5'-flanking DNA. Arch Biochem Biophys 334:309-24

Goodridge, A G; Klautky, S A; Fantozzi, D A et al. (1996) Nutritional and hormonal regulation of expression of the gene for malic enzyme. Prog Nucleic Acid Res Mol Biol 52:89-122