Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK029786-04
Application #
3229028
Study Section
Physiology Study Section (PHY)
Project Start
1981-05-01
Project End
1986-07-31
Budget Start
1986-03-01
Budget End
1986-07-31
Support Year
4
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Claiborne, J B; Blackston, C R; Choe, K P et al. (1999) A mechanism for branchial acid excretion in marine fish: identification of multiple Na+/H+ antiporter (NHE) isoforms in gills of two seawater teleosts. J Exp Biol 202:315-24
Dawson, D C; Smith, S S; Mansoura, M K (1999) CFTR: mechanism of anion conduction. Physiol Rev 79:S47-75
Mansoura, M K; Dawson, D C (1998) 2 barrier-1 site pore: an interactive spreadsheet model for two permeating ions. Comput Biol Med 28:255-73
Mansoura, M K; Smith, S S; Choi, A D et al. (1998) Cystic fibrosis transmembrane conductance regulator (CFTR) anion binding as a probe of the pore. Biophys J 74:1320-32
Harris, S P; Strong, T V; Wys, N et al. (1997) Epithelial localization of a reptilian Na+/H+ exchanger homologous to NHE-1. Am J Physiol 272:G1594-606
Wilkinson, D J; Strong, T V; Mansoura, M K et al. (1997) CFTR activation: additive effects of stimulatory and inhibitory phosphorylation sites in the R domain. Am J Physiol 273:L127-33
Nasr, S Z; Strong, T V; Mansoura, M K et al. (1996) Novel missense mutation (G314R) in a cystic fibrosis patient with hepatic failure. Hum Mutat 7:151-4
Wilkinson, D J; Mansoura, M K; Watson, P Y et al. (1996) CFTR: the nucleotide binding folds regulate the accessibility and stability of the activated state. J Gen Physiol 107:103-19
Engelhardt, J F; Smith, S S; Allen, E et al. (1994) Coupled secretion of chloride and mucus in skin of Xenopus laevis: possible role for CFTR. Am J Physiol 267:C491-500
Post, M A; Dawson, D C (1994) Basolateral Na(+)-H+ antiporter. Mechanisms of electroneutral and conductive ion transport. J Gen Physiol 103:895-916

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