Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK030444-12
Application #
2138384
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1982-03-01
Project End
1997-07-31
Budget Start
1994-08-01
Budget End
1997-07-31
Support Year
12
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Chen, Monica C; Solomon, Travis E; Kui, Robert et al. (2002) Apical EGF receptors regulate epithelial barrier to gastric acid: endogenous TGF-alpha is an essential facilitator. Am J Physiol Gastrointest Liver Physiol 283:G1098-106
Chen, M C; Goliger, J; Bunnett, N et al. (2001) Apical and basolateral EGF receptors regulate gastric mucosal paracellular permeability. Am J Physiol Gastrointest Liver Physiol 280:G264-72
Kato, K; Chen, M C; Nguyen, M et al. (1999) Effects of growth factors and trefoil peptides on migration and replication in primary oxyntic cultures. Am J Physiol 276:G1105-16
Schepp, W; Chan, C B; Giraud, A S et al. (1994) Effects of prostaglandins on gastrin release from canine antral mucosal cells in primary culture. Am J Physiol 266:G194-200
Chen, M C; Chang, A; Buhl, T et al. (1994) Apical acidification induces paracellular injury in canine gastric mucosal monolayers. Am J Physiol 267:G1012-20
Chuang, C N; Chen, M C; Soll, A H (1994) The pathways regulating acid secretion: the view from the isolated cell. Yale J Biol Med 67:107-12
Chen, M C; Lee, A T; Karnes, W E et al. (1993) Paracrine control of gastric epithelial cell growth in culture by transforming growth factor-alpha. Am J Physiol 264:G390-6
Chuang, C N; Chen, M C; Soll, A H (1992) Regulation of histamine release from oxyntic mucosa. Yale J Biol Med 65:753-9;discussion 827-9
Chuang, C N; Chen, M C; Soll, A H (1991) Gastrin-histamine interactions: direct and paracrine elements. Scand J Gastroenterol Suppl 180:95-103
Soll, A H (1990) Pathogenesis of peptic ulcer and implications for therapy. N Engl J Med 322:909-16

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