Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
7R01DK031507-06
Application #
3230132
Study Section
Biophysics and Biophysical Chemistry B Study Section (BBCB)
Project Start
1986-12-01
Project End
1989-04-30
Budget Start
1986-12-01
Budget End
1988-04-30
Support Year
6
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Sprang, S R; Madsen, N B; Withers, S G (1992) Multiple phosphate positions in the catalytic site of glycogen phosphorylase: structure of the pyridoxal-5'-pyrophosphate coenzyme-substrate analog. Protein Sci 1:1100-11
Sprang, S R; Withers, S G; Goldsmith, E J et al. (1991) Structural basis for the activation of glycogen phosphorylase b by adenosine monophosphate. Science 254:1367-71
Goldsmith, E J; Sprang, S R; Hamlin, R et al. (1989) Domain separation in the activation of glycogen phosphorylase a. Science 245:528-32
Sprang, S R; Acharya, K R; Goldsmith, E J et al. (1988) Structural changes in glycogen phosphorylase induced by phosphorylation. Nature 336:215-21
Sprang, S; Goldsmith, E; Fletterick, R (1987) Structure of the nucleotide activation switch in glycogen phosphorylase a. Science 237:1012-9
Rath, V L; Newgard, C B; Sprang, S R et al. (1987) Modeling the biochemical differences between rabbit muscle and human liver phosphorylase. Proteins 2:225-35