Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK035083-10
Application #
2139475
Study Section
Endocrinology Study Section (END)
Project Start
1987-08-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Sidney Kimmel Cancer Center
Department
Type
DUNS #
City
San Diego
State
CA
Country
United States
Zip Code
92121
Piedrafita, F J; Pfahl, M (1997) Retinoid-induced apoptosis and Sp1 cleavage occur independently of transcription and require caspase activation. Mol Cell Biol 17:6348-58
Piedrafita, F J; Ortiz, M A; Pfahl, M (1995) Thyroid hormone receptor-beta mutants associated with generalized resistance to thyroid hormone show defects in their ligand-sensitive repression function. Mol Endocrinol 9:1533-48
Piedrafita, F J; Bendik, I; Ortiz, M A et al. (1995) Thyroid hormone receptor homodimers can function as ligand-sensitive repressors. Mol Endocrinol 9:563-78
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Hermann, T; Hoffmann, B; Zhang, X K et al. (1992) Heterodimeric receptor complexes determine 3,5,3'-triiodothyronine and retinoid signaling specificities. Mol Endocrinol 6:1153-62
Yang-Yen, H F; Zhang, X K; Graupner, G et al. (1991) Antagonism between retinoic acid receptors and AP-1: implications for tumor promotion and inflammation. New Biol 3:1206-19
Zhang, X K; Wills, K N; Husmann, M et al. (1991) Novel pathway for thyroid hormone receptor action through interaction with jun and fos oncogene activities. Mol Cell Biol 11:6016-25

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