Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK035830-02
Application #
3234084
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1985-07-01
Project End
1988-06-30
Budget Start
1986-07-01
Budget End
1987-06-30
Support Year
2
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of Utah
Department
Type
Schools of Medicine
DUNS #
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
Cheung, A K; Parker, C J; Ren, K et al. (1996) Increased lipase inhibition in uremia: identification of pre-beta-HDL as a major inhibitor in normal and uremic plasma. Kidney Int 49:1360-71
Cheung, A K; Parker, C J; Hohnholt, M (1994) Soluble complement receptor type 1 inhibits complement activation induced by hemodialysis membranes in vitro. Kidney Int 46:1680-7
Cheung, A K; Parker, C J; Hohnholt, M (1993) Beta2 integrins are required for neutrophil degranulation induced by hemodialysis membranes. Kidney Int 43:649-60
Faucette, K J; Fitzgerald, L A; Liu, L et al. (1993) Characterization of the interactions between procoagulant albumin and human endothelial cells. Blood 82:2684-92
Holguin, M H; Martin, C B; Weis, J H et al. (1993) Enhanced expression of the complement regulatory protein, membrane inhibitor of reactive lysis (CD59), is regulated at the level of transcription. Blood 82:968-77
Gubler, D B; Wilson, B D; Parker, C J et al. (1993) Regulation of endothelial cell protein C activation and fibrinolysis by procoagulant albumin. Thromb Res 70:459-69
Holguin, M H; Martin, C B; Bernshaw, N J et al. (1992) Analysis of the effects of activation of the alternative pathway of complement on erythrocytes with an isolated deficiency of decay accelerating factor. J Immunol 148:498-502
Ezzell, J L; Parker, C J (1992) Cell-surface regulation of the human alternative pathway of complement. Sheep but not rabbit erythrocytes express factor I-dependent cofactor activity. Scand J Immunol 36:79-87
Faucette, K J; Parker, C J; McCluskey, T et al. (1992) Induction of tissue factor activity in endothelial cells and monocytes by a modified form of albumin present in normal human plasma. Blood 79:2888-95
Wilcox, L A; Ezzell, J L; Bernshaw, N J et al. (1991) Molecular basis of the enhanced susceptibility of the erythrocytes of paroxysmal nocturnal hemoglobinuria to hemolysis in acidified serum. Blood 78:820-9

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