Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
2R01DK036714-07A2
Application #
2139855
Study Section
Biochemical Endocrinology Study Section (BCE)
Project Start
1986-01-01
Project End
2000-01-31
Budget Start
1996-02-07
Budget End
1997-01-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
St. Luke's-Roosevelt Institute for Health Sciences
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10019
Rosner, W; Hryb, D J; Khan, M S et al. (1999) Sex hormone-binding globulin mediates steroid hormone signal transduction at the plasma membrane. J Steroid Biochem Mol Biol 69:481-5
Nakhla, A M; Leonard, J; Hryb, D J et al. (1999) Sex hormone-binding globulin receptor signal transduction proceeds via a G protein. Steroids 64:213-6
Rosner, W; Hryb, D J; Khan, M S et al. (1998) Androgens, estrogens, and second messengers. Steroids 63:278-81
Nakhla, A M; Romas, N A; Rosner, W (1997) Estradiol activates the prostate androgen receptor and prostate-specific antigen secretion through the intermediacy of sex hormone-binding globulin. J Biol Chem 272:6838-41
Nakhla, A M; Rosner, W (1996) Stimulation of prostate cancer growth by androgens and estrogens through the intermediacy of sex hormone-binding globulin. Endocrinology 137:4126-9
Blithe, D L; Khan, M S; Rosner, W (1992) Comparison of the carbohydrate composition of rat and human corticosteroid-binding globulin: species specific glycosylation. J Steroid Biochem Mol Biol 42:475-8
Rosner, W; Hryb, D J; Khan, M S et al. (1992) Sex hormone-binding globulin. Binding to cell membranes and generation of a second messenger. J Androl 13:101-6
Rosner, W; Hryb, D J; Khan, M S et al. (1991) Sex hormone-binding globulin: anatomy and physiology of a new regulatory system. J Steroid Biochem Mol Biol 40:813-20
Hryb, D J; Khan, M S; Romas, N A et al. (1990) The control of the interaction of sex hormone-binding globulin with its receptor by steroid hormones. J Biol Chem 265:6048-54
Khan, M S; Hryb, D J; Hashim, G A et al. (1990) Delineation and synthesis of the membrane receptor-binding domain of sex hormone-binding globulin. J Biol Chem 265:18362-5

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