Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK037879-05S1
Application #
3236876
Study Section
Pathology A Study Section (PTHA)
Project Start
1986-12-15
Project End
1994-11-30
Budget Start
1991-06-25
Budget End
1991-11-30
Support Year
5
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Washington University
Department
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Wu, X; Tiwari, A K; Issekutz, T B et al. (1996) Differing roles of CD18 and VLA-4 in leukocyte migration/activation during anti-GBM nephritis. Kidney Int 50:462-72
Wu, X; Dolecki, G J; Lefkowith, J B (1995) GRO chemokines: a transduction, integration, and amplification mechanism in acute renal inflammation. Am J Physiol 269:F248-56
Scandrett, A L; Kissane, J; Lefkowith, J B (1995) Acute inflammation is the harbinger of glomerulosclerosis in anti-glomerular basement membrane nephritis. Am J Physiol 268:F258-65
Wu, X; Helfrich, M H; Horton, M A et al. (1994) Fibrinogen mediates platelet-polymorphonuclear leukocyte cooperation during immune-complex glomerulonephritis in rats. J Clin Invest 94:928-36
Wu, X; Wittwer, A J; Carr, L S et al. (1994) Cytokine-induced neutrophil chemoattractant mediates neutrophil influx in immune complex glomerulonephritis in rat. J Clin Invest 94:337-44
Wu, X; Pippin, J; Lefkowith, J B (1993) Attenuation of immune-mediated glomerulonephritis with an anti-CD11b monoclonal antibody. Am J Physiol 264:F715-21
Wu, X; Pippin, J; Lefkowith, J B (1993) Platelets and neutrophils are critical to the enhanced glomerular arachidonate metabolism in acute nephrotoxic nephritis in rats. J Clin Invest 91:766-73
Lefkowith, J B; Pippin, J; Nagamatsu, T et al. (1992) Urinary eicosanoids and the assessment of glomerular inflammation. J Am Soc Nephrol 2:1560-7
Porras-Reyes, B H; Schreiner, G F; Lefkowith, J B et al. (1992) Essential fatty acids are not required for wound healing. Prostaglandins Leukot Essent Fatty Acids 45:293-8
Nagamatsu, T; Pippin, J; Schreiner, G F et al. (1992) Paradoxical exacerbation of leukocyte-mediated glomerulonephritis with cyclooxygenase inhibition. Am J Physiol 263:F228-36

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