Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK040605-08
Application #
2141414
Study Section
Metabolism Study Section (MET)
Project Start
1989-07-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Pennsylvania State University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
129348186
City
Hershey
State
PA
Country
United States
Zip Code
17033
Diamanti-Kandarakis, Evanthia; Dunaif, Andrea (2012) Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications. Endocr Rev 33:981-1030
Sam, Susan; Sung, Yeon-Ah; Legro, Richard S et al. (2008) Evidence for pancreatic beta-cell dysfunction in brothers of women with polycystic ovary syndrome. Metabolism 57:84-9
Sam, Susan; Coviello, Andrea D; Sung, Yeon-Ah et al. (2008) Metabolic phenotype in the brothers of women with polycystic ovary syndrome. Diabetes Care 31:1237-41
Corbould, Anne; Dunaif, Andrea (2007) The adipose cell lineage is not intrinsically insulin resistant in polycystic ovary syndrome. Metabolism 56:716-22
Corbould, Anne; Zhao, Haiyan; Mirzoeva, Salida et al. (2006) Enhanced mitogenic signaling in skeletal muscle of women with polycystic ovary syndrome. Diabetes 55:751-9
Corbould, Anne; Kim, Young-Bum; Youngren, Jack F et al. (2005) Insulin resistance in the skeletal muscle of women with PCOS involves intrinsic and acquired defects in insulin signaling. Am J Physiol Endocrinol Metab 288:E1047-54
Legro, Richard S; Urbanek, Margrit; Kunselman, Allen R et al. (2002) Self-selected women with polycystic ovary syndrome are reproductively and metabolically abnormal and undertreated. Fertil Steril 78:51-7
Legro, Richard S; Kunselman, Allen R; Demers, Lawrence et al. (2002) Elevated dehydroepiandrosterone sulfate levels as the reproductive phenotype in the brothers of women with polycystic ovary syndrome. J Clin Endocrinol Metab 87:2134-8
Legro, Richard S; Bentley-Lewis, Rhonda; Driscoll, Deborah et al. (2002) Insulin resistance in the sisters of women with polycystic ovary syndrome: association with hyperandrogenemia rather than menstrual irregularity. J Clin Endocrinol Metab 87:2128-33
Solomon, Caren G; Hu, Frank B; Dunaif, Andrea et al. (2002) Menstrual cycle irregularity and risk for future cardiovascular disease. J Clin Endocrinol Metab 87:2013-7

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