Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK041606-05
Application #
2141828
Study Section
Special Emphasis Panel (ZRG3-ET-2 (03))
Project Start
1991-04-15
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Pediatrics
Type
Other Domestic Higher Education
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Pan, Bih Fang; Nelson, J Arly (2007) Dihydrodiol dehydrogenase in drug resistance and sensitivity of human carcinomas. Cancer Chemother Pharmacol 59:697-702
Chen, Rong; Jonker, Johan W; Nelson, J Arly (2002) Renal organic cation and nucleoside transport. Biochem Pharmacol 64:185-90
Chen, R; Nelson, J A (2000) Role of organic cation transporters in the renal secretion of nucleosides. Biochem Pharmacol 60:215-9
Pan, B F; Sweet, D H; Pritchard, J B et al. (1999) A transfected cell model for the renal toxin transporter, rOCT2. Toxicol Sci 47:181-6
Chen, R; Pan, B F; Sakurai, M et al. (1999) A nucleoside-sensitive organic cation transporter in opossum kidney cells. Am J Physiol 276:F323-8
Elfarra, A A; Duescher, R J; Hwang, I Y et al. (1995) Targeting 6-thioguanine to the kidney with S-(guanin-6-yl)-L-cysteine. J Pharmacol Exp Ther 274:1298-304
Nelson, J A; Dutt, A; Allen, L H et al. (1995) Functional expression of the renal organic cation transporter and P-glycoprotein in Xenopus laevis oocytes. Cancer Chemother Pharmacol 37:187-9
Pan, B F; Dutt, A; Nelson, J A (1994) Enhanced transepithelial flux of cimetidine by Madin-Darby canine kidney cells overexpressing human P-glycoprotein. J Pharmacol Exp Ther 270:1-7
Dutt, A; Heath, L A; Nelson, J A (1994) P-glycoprotein and organic cation secretion by the mammalian kidney. J Pharmacol Exp Ther 269:1254-60
Dutt, A; Priebe, T S; Teeter, L D et al. (1992) Postnatal development of organic cation transport and mdr gene expression in mouse kidney. J Pharmacol Exp Ther 261:1222-30