Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK041678-05
Application #
2141862
Study Section
Nutrition Study Section (NTN)
Project Start
1990-08-10
Project End
1999-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Ko, Cynthia W; Schulte, Scott J; Lee, Sum P (2005) Biliary sludge is formed by modification of hepatic bile by the gallbladder mucosa. Clin Gastroenterol Hepatol 3:672-8
Haigh, W G; Lee, S P (2001) Identification of oxysterols in human bile and pigment gallstones. Gastroenterology 121:118-23
Wrenn, S P; Gudheti, M; Veleva, A N et al. (2001) Characterization of model bile using fluorescence energy transfer from dehydroergosterol to dansylated lecithin. J Lipid Res 42:923-34
Ko, C W; Sekijima, J H; Lee, S P (1999) Biliary sludge. Ann Intern Med 130:301-11
Wrenn, S P; Kaler, E W; Lee, S P (1999) A fluorescence energy transfer study of lecithin-cholesterol vesicles in the presence of phospholipase C. J Lipid Res 40:1483-94
Ko, C W; Lee, S P (1999) Gallstone formation. Local factors. Gastroenterol Clin North Am 28:99-115
Ko, C W; Kowdley, K V; Haigh, W G et al. (1998) Biliary lipid composition after liver transplantation: effect of allograft function and cyclosporine. Liver Transpl Surg 4:258-64
Klinkspoor, J H; Yoshida, T; Lee, S P (1998) Bile salts stimulate mucin secretion by cultured dog gallbladder epithelial cells independent of their detergent effect. Biochem J 332 ( Pt 1):257-62
Luk, A S; Kaler, E W; Lee, S P (1998) Protein lipid interaction in bile: effects of biliary proteins on the stability of cholesterol-lecithin vesicles. Biochim Biophys Acta 1390:282-92
Luk, A S; Kaler, E W; Lee, S P (1997) Structural mechanisms of bile salt-induced growth of small unilamellar cholesterol-lecithin vesicles. Biochemistry 36:5633-44

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