Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK042552-05S1
Application #
2142378
Study Section
Endocrinology Study Section (END)
Project Start
1990-04-01
Project End
1995-03-31
Budget Start
1994-04-01
Budget End
1995-12-31
Support Year
5
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Georgetown University
Department
Biochemistry
Type
Schools of Dentistry
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057
Zhang, Shimin; Jonklaas, Jacqueline; Danielsen, Mark (2007) The glucocorticoid agonist activities of mifepristone (RU486) and progesterone are dependent on glucocorticoid receptor levels but not on EC50 values. Steroids 72:600-8
List, H J; Lozano, C; Lu, J et al. (1999) Comparison of chromatin remodeling and transcriptional activation of the mouse mammary tumor virus promoter by the androgen and glucocorticoid receptor. Exp Cell Res 250:414-22
Bonovich, M T; List, H J; Zhang, S et al. (1998) Identification of glucocorticoid receptor domains necessary for transcriptional activation of the mouse mammary tumor virus promoter integrated in the genome. Exp Cell Res 239:454-62
Lu, J; Danielsen, M (1996) A Stu I polymorphism in the human androgen receptor gene (AR). Clin Genet 49:323-4
Zhang, S; Liang, X; Danielsen, M (1996) Role of the C terminus of the glucocorticoid receptor in hormone binding and agonist/antagonist discrimination. Mol Endocrinol 10:24-34
Csikos, T; Tay, J; Danielsen, M (1995) Expression of the Xenopus laevis mineralocorticoid receptor during metamorphosis. Recent Prog Horm Res 50:393-6
Martin, M B; Garcia-Morales, P; Stoica, A et al. (1995) Effects of 12-O-tetradecanoylphorbol-13-acetate on estrogen receptor activity in MCF-7 cells. J Biol Chem 270:25244-51
Zhang, S; Danielsen, M (1995) 8-Br-cAMP does not convert antagonists of the glucocorticoid receptor into agonists. Recent Prog Horm Res 50:429-35
Rosenthal, D; Hong, T; Cherney, B et al. (1994) Expression and characterization of a fusion protein between the catalytic domain of poly(ADP-ribose) polymerase and the DNA binding domain of the glucocorticoid receptor. Biochem Biophys Res Commun 202:880-7
Chen, D; Kohli, K; Zhang, S et al. (1994) Phenylalanine-780 near the C-terminus of the mouse glucocorticoid receptor is important for ligand binding affinity and specificity. Mol Endocrinol 8:422-30

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