Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK043541-14
Application #
3244914
Study Section
Reproductive Biology Study Section (REB)
Project Start
1990-12-01
Project End
1995-04-30
Budget Start
1993-06-01
Budget End
1994-04-30
Support Year
14
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Type
Organized Research Units
DUNS #
City
Evanston
State
IL
Country
United States
Zip Code
60201
Zhang, Qiang; Zhou, Wei; Kundu, Shilajit et al. (2006) The leader sequence triggers and enhances several functions of clusterin and is instrumental in the progression of human prostate cancer in vivo and in vitro. BJU Int 98:452-60
Huang, Xuemei; Lee, Chung (2003) Regulation of stromal proliferation, growth arrest, differentiation and apoptosis in benign prostatic hyperplasia by TGF-beta. Front Biosci 8:s740-9
Wu, Angela J; Park, Irwin I; Zhaung, Lei et al. (2002) Response to a lethal dose of heat shock by a transient up-regulation of clusterin expression followed by down-regulation and apoptosis in prostate and bladder cancer cells. Prostate 53:277-85
Ilio, K Y; Park, I I; Pins, M R et al. (2001) Apoptotic activity of doxazosin on prostate stroma in vitro is mediated through an autocrine expression of TGF-beta1. Prostate 48:131-5
Kundu, S D; Kim, I Y; Yang, T et al. (2000) Absence of proximal duct apoptosis in the ventral prostate of transgenic mice carrying the C3(1)-TGF-beta type II dominant negative receptor. Prostate 43:118-24
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Lee, C; Sintich, S M; Mathews, E P et al. (1999) Transforming growth factor-beta in benign and malignant prostate. Prostate 39:285-90
Kassen, A; Sutkowski, D M; Ahn, H et al. (1996) Stromal cells of the human prostate: initial isolation and characterization. Prostate 28:89-97
Lee, C (1996) Role of androgen in prostate growth and regression: stromal-epithelial interaction. Prostate Suppl 6:52-6
Sensibar, J A; Sutkowski, D M; Raffo, A et al. (1995) Prevention of cell death induced by tumor necrosis factor alpha in LNCaP cells by overexpression of sulfated glycoprotein-2 (clusterin). Cancer Res 55:2431-7

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