Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK043640-03
Application #
2143117
Study Section
General Medicine B Study Section (GMB)
Project Start
1992-09-30
Project End
1997-09-30
Budget Start
1994-09-30
Budget End
1997-09-30
Support Year
3
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
005436803
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Dominguez, Jesus H; Soleimani, Manoocher; Batiuk, Thomas (2002) Studies of renal injury IV: The GLUT1 gene protects renal cells from cyclosporine A toxicity. Kidney Int 62:127-36
Dominguez, J H; Tang, N; Xu, W et al. (2000) Studies of renal injury III: lipid-induced nephropathy in type II diabetes. Kidney Int 57:92-104
Kamran, M; Peterson, R G; Dominguez, J H (1997) Overexpression of GLUT2 gene in renal proximal tubules of diabetic Zucker rats. J Am Soc Nephrol 8:943-8
Dominguez, J H; Hale, C C; Qulali, M (1996) Studies of renal injury. I. Gentamicin toxicity and expression of basolateral transporters. Am J Physiol 270:F245-53
Dominguez, J H; Song, B; Liu-Chen, S et al. (1996) Studies of renal injury. II. Activation of the glucose transporter 1 (GLUT1) gene and glycolysis in LLC-PK1 cells under Ca2+ stress. J Clin Invest 98:395-404
Soleimani, M; Singh, G; Bookstein, C et al. (1996) Inhibition of glycosylation decreases Na+/H+ exchange activity, blocks NHE-3 transport to the membrane, and increases NHE-3 mRNA expression in LLC-PK1 cells. J Lab Clin Med 127:565-73
Soleimani, M; Singh, G; Dominguez, J H et al. (1995) Long-term high osmolality activates Na(+)-H+ exchange and protein kinase C in aortic smooth muscle cells. Circ Res 76:530-5
Dominguez, J H; Song, B; Maianu, L et al. (1994) Gene expression of epithelial glucose transporters: the role of diabetes mellitus. J Am Soc Nephrol 5:S29-36
Dominguez, J H; Camp, K; Maianu, L et al. (1994) Molecular adaptations of GLUT1 and GLUT2 in renal proximal tubules of diabetic rats. Am J Physiol 266:F283-90