3alpha Hydroxysteroid Dehydrogenase Related Enzymes

Cheng, Kuo-Chi C.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 7R01DK044177-04
• Application #: 2143585
• Study Section: Endocrinology Study Section (END)
• Project Start: 1992-05-01
• Project End: 1997-01-31
• Budget Start: 1995-03-01
• Budget End: 1997-01-31
• Support Year: 4
• Fiscal Year: 1994

Institution

• Name: University of Connecticut
• Department: Pharmacology
• Type: Schools of Dentistry
• City: Farmington
• State: CT
• Country: United States
• Zip Code: 06030

Publications

Khanna, M; Qin, K N; Wang, R W et al. (1995) Substrate specificity, gene structure, and tissue-specific distribution of multiple human 3 alpha-hydroxysteroid dehydrogenases. J Biol Chem 270:20162-8

Khanna, M; Qin, K N; Klisak, I et al. (1995) Localization of multiple human dihydrodiol dehydrogenase (DDH1 and DDH2) and chlordecone reductase (CHDR) genes in chromosome 10 by the polymerase chain reaction and fluorescence in situ hybridization. Genomics 25:588-90

Cheng, K C; Lee, J; Khanna, M et al. (1994) Distribution and ontogeny of 3 alpha-hydroxysteroid dehydrogenase in the rat brain. J Steroid Biochem Mol Biol 50:85-9

Qin, K N; Cheng, K C (1994) Structure and tissue-specific expression of the aldo-keto reductase superfamily. Biochemistry 33:3223-8

Qin, K N; Khanna, M; Cheng, K C (1994) Structure of a gene coding for human dihydrodiol dehydrogenase/bile acid-binding protein. Gene 149:357-61

Qin, K N; New, M I; Cheng, K C (1993) Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase. J Steroid Biochem Mol Biol 46:673-9