Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK044948-03
Application #
2144197
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1993-08-15
Project End
1997-07-31
Budget Start
1995-08-01
Budget End
1997-07-31
Support Year
3
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California Irvine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
161202122
City
Irvine
State
CA
Country
United States
Zip Code
92697
Friess, H; Lu, Z; Riesle, E et al. (1998) Enhanced expression of TGF-betas and their receptors in human acute pancreatitis. Ann Surg 227:95-104
Ebert, M; Kasper, H U; Hernberg, S et al. (1998) Overexpression of platelet-derived growth factor (PDGF) B chain and type beta PDGF receptor in human chronic pancreatitis. Dig Dis Sci 43:567-74
Friess, H; Cantero, D; Graber, H et al. (1997) Enhanced urokinase plasminogen activation in chronic pancreatitis suggests a role in its pathogenesis. Gastroenterology 113:904-13
Kornmann, M; Ishiwata, T; Beger, H G et al. (1997) Fibroblast growth factor-5 stimulates mitogenic signaling and is overexpressed in human pancreatic cancer: evidence for autocrine and paracrine actions. Oncogene 15:1417-24
Estival, A; Monzat, V; Miquel, K et al. (1996) Differential regulation of fibroblast growth factor (FGF) receptor-1 mRNA and protein by two molecular forms of basic FGF. Modulation of FGFR-1 mRNA stability. J Biol Chem 271:5663-70
Horvath, L Z; Friess, H; Schilling, M et al. (1996) Altered expression of transforming growth factor-beta S in chronic renal rejection. Kidney Int 50:489-98
Bergmann, U; Funatomi, H; Kornmann, M et al. (1996) Increased expression of insulin receptor substrate-1 in human pancreatic cancer. Biochem Biophys Res Commun 220:886-90
Friess, H; Berberat, P; Schilling, M et al. (1996) Pancreatic cancer: the potential clinical relevance of alterations in growth factors and their receptors. J Mol Med 74:35-42
Ebert, M; Yokoyama, M; Friess, H et al. (1995) Induction of platelet-derived growth factor A and B chains and over-expression of their receptors in human pancreatic cancer. Int J Cancer 62:529-35
Siddiqi, I; Funatomi, H; Kobrin, M S et al. (1995) Increased expression of keratinocyte growth factor in human pancreatic cancer. Biochem Biophys Res Commun 215:309-15

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