Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK045301-01S1
Application #
3246820
Study Section
Nutrition Study Section (NTN)
Project Start
1992-09-30
Project End
1995-09-29
Budget Start
1993-07-01
Budget End
1993-09-29
Support Year
1
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of California Davis
Department
Type
Schools of Medicine
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618
Halsted, Charles H; Villanueva, Jesus A; Devlin, Angela M et al. (2002) Interactions of ethanol and folate deficiency in development of alcoholic liver disease in the micropig. Trans Am Clin Climatol Assoc 113:151-62; discussion 162-3
Halsted, Charles H; Villanueva, Jesus A; Devlin, Angela M et al. (2002) Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig. Proc Natl Acad Sci U S A 99:10072-7
Halsted, Charles H; Villanueva, Jesus A; Devlin, Angela M (2002) Folate deficiency, methionine metabolism, and alcoholic liver disease. Alcohol 27:169-72
Villanueva, J A; Devlin, A M; Halsted, C H (2001) Reduced folate carrier: tissue distribution and effects of chronic ethanol intake in the micropig. Alcohol Clin Exp Res 25:415-20
Devlin, A M; Ling, E H; Peerson, J M et al. (2000) Glutamate carboxypeptidase II: a polymorphism associated with lower levels of serum folate and hyperhomocysteinemia. Hum Mol Genet 9:2837-44
Halsted, C H; Ling, E H; Luthi-Carter, R et al. (1998) Folylpoly-gamma-glutamate carboxypeptidase from pig jejunum. Molecular characterization and relation to glutamate carboxypeptidase II. J Biol Chem 273:20417-24
Villanueva, J; Ling, E H; Chandler, C J et al. (1998) Membrane and tissue distribution of folate binding protein in pig. Am J Physiol 275:R1503-10
Van Hoozen, C M; Ling, E H; Halsted, C H (1996) Folate binding protein: molecular characterization and transcript distribution in pig liver, kidney and jejunum. Biochem J 319 ( Pt 3):725-9