Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK045485-04
Application #
2144725
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Project Start
1992-09-30
Project End
1997-03-31
Budget Start
1995-09-30
Budget End
1997-03-31
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199

  Publications

Goustin, Anton-Scott; Abou-Samra, Abdul B (2011) The ""thrifty"" gene encoding Ahsg/Fetuin-A meets the insulin receptor: Insights into the mechanism of insulin resistance. Cell Signal 23:980-90
Tawfeek, Hesham A W; Abou-Samra, Abdul B (2008) Negative regulation of parathyroid hormone (PTH)-activated phospholipase C by PTH/PTH-related peptide receptor phosphorylation and protein kinase A. Endocrinology 149:4016-23
Bounoutas, George S; Tawfeek, Hesham; Frohlich, Leopold F et al. (2006) Impact of impaired receptor internalization on calcium homeostasis in knock-in mice expressing a phosphorylation-deficient parathyroid hormone (PTH)/PTH-related peptide receptor. Endocrinology 147:4674-9
Williams, L J; Abou-Samra, A B (2000) The transcription factors SP1 and MAZ regulate expression of the parathyroid hormone/parathyroid hormone-related peptide receptor gene. J Mol Endocrinol 25:309-19
Giannoukos, G; Williams, L J; Chilco, P J et al. (1999) Characterization of an element within the rat parathyroid hormone/parathyroid hormone-related peptide receptor gene promoter that enhances expression in osteoblastic osteosarcoma 17/2.8 cells. Biochem Biophys Res Commun 258:336-40
Urena, P; Iida-Klein, A; Kong, X F et al. (1994) Regulation of parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acid by glucocorticoids and PTH in ROS 17/2.8 and OK cells. Endocrinology 134:451-6
Fukayama, S; Schipani, E; Juppner, H et al. (1994) Role of protein kinase-A in homologous down-regulation of parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acid in human osteoblast-like SaOS-2 cells. Endocrinology 134:1851-8