Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
7R01DK045740-04
Application #
2144969
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1992-09-30
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1994
Total Cost
Indirect Cost

  Institution

Name
University of Virginia
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904

  Publications

Redlitz, Karen H; Yamshchikov, Vladimir F; Cominelli, Fabio (2004) Differential contribution of IL-1Ra isoforms to allele-specific IL-1Ra mRNA accumulation. J Interferon Cytokine Res 24:253-60
Yamshchikov, Vladimir F; Mishina, Margarita; Cominelli, Fabio (2002) A possible role of IL-1ra 3'-untranslated region in modulation of protein production. Cytokine 17:98-107
Compton, R F; Sandborn, W J; Yang, H et al. (1997) A new syndrome of Crohn's disease and pachydermoperiostosis in a family. Gastroenterology 112:241-9
Cominelli, F; Pizarro, T T (1996) Interleukin-1 and interleukin-1 receptor antagonist in inflammatory bowel disease. Aliment Pharmacol Ther 10 Suppl 2:49-53;discussion 54
Laine, L; Sloane, R; Ferretti, M et al. (1995) A randomized double-blind comparison of placebo, etodolac, and naproxen on gastrointestinal injury and prostaglandin production. Gastrointest Endosc 42:428-33
Casini-Raggi, V; Kam, L; Chong, Y J et al. (1995) Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease. A novel mechanism of chronic intestinal inflammation. J Immunol 154:2434-40
Casini-Raggi, V; Monsacchi, L; Vosbeck, K et al. (1995) Anti-inflammatory effects of CGP 47969A, a novel inhibitor of proinflammatory cytokine synthesis, in rabbit immune colitis. Gastroenterology 109:812-8
Ferretti, M; Casini-Raggi, V; Pizarro, T T et al. (1994) Neutralization of endogenous IL-1 receptor antagonist exacerbates and prolongs inflammation in rabbit immune colitis. J Clin Invest 94:449-53
Cominelli, F; Bortolami, M; Pizarro, T T et al. (1994) Rabbit interleukin-1 receptor antagonist. Cloning, expression, functional characterization, and regulation during intestinal inflammation. J Biol Chem 269:6962-71