Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
7R01DK046626-04
Application #
2145884
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1993-09-01
Project End
1997-08-31
Budget Start
1996-06-20
Budget End
1996-08-31
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Children's Hospital & Res Ctr at Oakland
Department
Type
DUNS #
City
Oakland
State
CA
Country
United States
Zip Code
94609
Thomson, G; Valdes, A M; Noble, J A et al. (2007) Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis. Tissue Antigens 70:110-27
Valdes, Ana M; Erlich, Henry A; Noble, Janelle A (2005) Human leukocyte antigen class I B and C loci contribute to Type 1 Diabetes (T1D) susceptibility and age at T1D onset. Hum Immunol 66:301-13
Valdes, A M; Wapelhorst, B; Concannon, P et al. (2005) Extended DR3-D6S273-HLA-B haplotypes are associated with increased susceptibility to type 1 diabetes in US Caucasians. Tissue Antigens 65:115-9
Noble, Janelle A; White, Amy M; Lazzeroni, Laura C et al. (2003) A polymorphism in the TCF7 gene, C883A, is associated with type 1 diabetes. Diabetes 52:1579-82
Single, Richard M; Meyer, Diogo; Hollenbach, Jill A et al. (2002) Haplotype frequency estimation in patient populations: the effect of departures from Hardy-Weinberg proportions and collapsing over a locus in the HLA region. Genet Epidemiol 22:186-95
Noble, Janelle A; Valdes, Ana M; Bugawan, Teodorica L et al. (2002) The HLA class I A locus affects susceptibility to type 1 diabetes. Hum Immunol 63:657-64
Park, Y S; She, J X; Noble, J A et al. (2001) Transracial evidence for the influence of the homologous HLA DR-DQ haplotype on transmission of HLA DR4 haplotypes to diabetic children. Tissue Antigens 57:185-91
Valdes, A M; Noble, J A; Genin, E et al. (2001) Modeling of HLA class II susceptibility to Type I diabetes reveals an effect associated with DPB1. Genet Epidemiol 21:212-23
Noble, J A; Valdes, A M; Thomson, G et al. (2000) The HLA class II locus DPB1 can influence susceptibility to type 1 diabetes. Diabetes 49:121-5
Redondo, M J; Kawasaki, E; Mulgrew, C L et al. (2000) DR- and DQ-associated protection from type 1A diabetes: comparison of DRB1*1401 and DQA1*0102-DQB1*0602*. J Clin Endocrinol Metab 85:3793-7

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