Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK046807-01S1
Application #
3248154
Study Section
Endocrinology Study Section (END)
Project Start
1993-07-15
Project End
1997-06-30
Budget Start
1993-07-16
Budget End
1994-06-30
Support Year
1
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Yale University
Department
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Keeler, Camille; Hodsdon, Michael E; Dannies, Priscilla S (2004) Is there structural specificity in the reversible protein aggregates that are stored in secretory granules? J Mol Neurosci 22:43-9
Keeler, Camille; Dannies, Priscilla S; Hodsdon, Michael E (2003) The tertiary structure and backbone dynamics of human prolactin. J Mol Biol 328:1105-21
Sankoorikal, Binu-John; Zhu, Yong Lian; Hodsdon, Michael E et al. (2002) Aggregation of human wild-type and H27A-prolactin in cells and in solution: roles of Zn(2+), Cu(2+), and pH. Endocrinology 143:1302-9
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Lee, M S; Zhu, Y L; Chang, J E et al. (2001) Acquisition of Lubrol insolubility, a common step for growth hormone and prolactin in the secretory pathway of neuroendocrine cells. J Biol Chem 276:715-21
Dannies, P S (2000) Protein folding and deficiencies caused by dominant-negative mutants of hormones. Vitam Horm 58:26-Jan
Lee, M S; Wajnrajch, M P; Kim, S S et al. (2000) Autosomal dominant growth hormone (GH) deficiency type II: the Del32-71-GH deletion mutant suppresses secretion of wild-type GH. Endocrinology 141:883-90
Lee, M S; Dirkx Jr, R; Solimena, M et al. (1998) Stabilization of the receptor protein tyrosine phosphatase-like protein ICA512 in GH4C1 cells upon treatment with estradiol, insulin, and epidermal growth factor. Endocrinology 139:2727-33
Sun, Z; Lee, M S; Rhee, H K et al. (1997) Inefficient secretion of human H27A-prolactin, a mutant that does not bind Zn2+. Mol Endocrinol 11:1544-51
Sun, Z; Li, P S; Dannies, P S et al. (1996) Properties of human prolactin (PRL) and H27A-PRL, a mutant that does not bind Zn++. Mol Endocrinol 10:265-71

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