Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK046942-02
Application #
2146249
Study Section
Metabolism Study Section (MET)
Project Start
1995-01-01
Project End
1998-12-31
Budget Start
1996-05-18
Budget End
1996-12-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Stanford University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Khor, Victor K; Shen, Wen-Jun; Kraemer, Fredric B (2013) Lipid droplet metabolism. Curr Opin Clin Nutr Metab Care 16:632-7
Shen, Wen-Jun; Patel, Shailja; Eriksson, John E et al. (2010) Vimentin is a functional partner of hormone sensitive lipase and facilitates lipolysis. J Proteome Res 9:1786-94
Shen, Wen-Jun; Patel, Shailja; Miyoshi, Hideaki et al. (2009) Functional interaction of hormone-sensitive lipase and perilipin in lipolysis. J Lipid Res 50:2306-13
Shen, Wen-Jun; Patel, Shailja; Yu, Zaixin et al. (2007) Effects of rosiglitazone and high fat diet on lipase/esterase expression in adipose tissue. Biochim Biophys Acta 1771:177-84
Shen, Wen-Jun; Liang, Yu; Wang, Jenny et al. (2007) Regulation of hormone-sensitive lipase in islets. Diabetes Res Clin Pract 75:14-26
Wang, Jining; Shen, Wen-Jun; Patel, Shailja et al. (2005) Mutational analysis of the ""regulatory module"" of hormone-sensitive lipase. Biochemistry 44:1953-9
Smith, Anne J; Sanders, Mark A; Thompson, Brian R et al. (2004) Physical association between the adipocyte fatty acid-binding protein and hormone-sensitive lipase: a fluorescence resonance energy transfer analysis. J Biol Chem 279:52399-405
Kraemer, Fredric B; Shen, Wen-Jun; Harada, Kenji et al. (2004) Hormone-sensitive lipase is required for high-density lipoprotein cholesteryl ester-supported adrenal steroidogenesis. Mol Endocrinol 18:549-57
Shen, Wen-Jun; Patel, Shailja; Natu, Vanita et al. (2003) Interaction of hormone-sensitive lipase with steroidogenic acute regulatory protein: facilitation of cholesterol transfer in adrenal. J Biol Chem 278:43870-6
Ke, Yaohuang; Qiu, Jun; Ogus, Scott et al. (2003) Overexpression of leptin in transgenic mice leads to decreased basal lipolysis, PKA activity, and perilipin levels. Biochem Biophys Res Commun 312:1165-70

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