Molecular Characterization of H2 Receptor Dual Signaling

Delvalle, John

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 5R01DK047434-03
• Application #: 2147045
• Study Section: General Medicine A Subcommittee 2 (GMA)
• Project Start: 1994-09-30
• Project End: 1997-08-31
• Budget Start: 1996-09-11
• Budget End: 1997-08-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of Michigan Ann Arbor
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 791277940
• City: Ann Arbor
• State: MI
• Country: United States
• Zip Code: 48109

Publications

Wang, L D; Gantz, I; Butler, K et al. (2000) Histamine H2 receptor mediated dual signaling: mapping of structural requirements using beta2 adrenergic chimeric receptors. Biochem Biophys Res Commun 276:539-45

Wang, L D; Hoeltzel, M; Gantz, I et al. (1998) Characterization of the histamine H2 receptor structural components involved in dual signaling. J Pharmacol Exp Ther 285:573-8

Nagahara, A; Wang, L; Del Valle, J et al. (1998) Regulation of c-Jun NH2-terminal kinases in isolated canine gastric parietal cells. Am J Physiol 275:G740-8

Chey, W D; Fisher, L; Elta, G H et al. (1997) Bismuth subsalicylate instead of metronidazole with lansoprazole and clarithromycin for Helicobacter pylori infection: a randomized trial. Am J Gastroenterol 92:1483-6

Beales, I; Blaser, M J; Srinivasan, S et al. (1997) Effect of Helicobacter pylori products and recombinant cytokines on gastrin release from cultured canine G cells. Gastroenterology 113:465-71

Chey, W D; Woods, M; Scheiman, J M et al. (1997) Lansoprazole and ranitidine affect the accuracy of the 14C-urea breath test by a pH-dependent mechanism. Am J Gastroenterol 92:446-50

DelValle, J (1997) The stomach as an endocrine organ. Digestion 58 Suppl 1:4-7

Del Valle, J; Gantz, I (1997) Novel insights into histamine H2 receptor biology. Am J Physiol 273:G987-96

Wang, L; Wilson, E J; Osburn, J et al. (1996) Epidermal growth factor inhibits carbachol-stimulated canine parietal cell function via protein kinase C. Gastroenterology 110:469-77

Wang, L; Gantz, I; DelValle, J (1996) Histamine H2 receptor activates adenylate cyclase and PLC via separate GTP-dependent pathways. Am J Physiol 271:G613-20