Igf Axis Abnormalities in Bph

Cohen, Pinchas

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 2R01DK047591-04
• Application #: 2147334
• Study Section: Reproductive Endocrinology Study Section (REN)
• Project Start: 1993-09-30
• Project End: 2000-08-31
• Budget Start: 1996-09-08
• Budget End: 1997-08-31
• Support Year: 4
• Fiscal Year: 1996

Institution

• Name: Children's Hospital of Philadelphia
• DUNS #: 073757627
• City: Philadelphia
• State: PA
• Country: United States
• Zip Code: 19104

Publications

Shim, Melanie L; Levitt Katz, Lorraine E; Davis, Jason et al. (2004) Insulin-like growth factor binding protein-3 is a novel mediator of apoptosis in insulin-secreting cells. Growth Horm IGF Res 14:216-25

Wetterau, Lawrence A; Francis, Malik J; Ma, Liqun et al. (2003) Insulin-like growth factor I stimulates telomerase activity in prostate cancer cells. J Clin Endocrinol Metab 88:3354-9

Moore, Michael G; Wetterau, Lawrence A; Francis, Malik J et al. (2003) Novel stimulatory role for insulin-like growth factor binding protein-2 in prostate cancer cells. Int J Cancer 105:14-9

Liu, Bingrong; Weinzimer, Stuart A; Gibson, Tara Beers et al. (2003) Type Ialpha collagen is an IGFBP-3 binding protein. Growth Horm IGF Res 13:89-97

Franklin, Sherry Lynn; Ferry Jr, Robert J; Cohen, Pinchas (2003) Rapid insulin-like growth factor (IGF)-independent effects of IGF binding protein-3 on endothelial cell survival. J Clin Endocrinol Metab 88:900-7

Ngo, Tung H; Barnard, R James; Cohen, Pinchas et al. (2003) Effect of isocaloric low-fat diet on human LAPC-4 prostate cancer xenografts in severe combined immunodeficient mice and the insulin-like growth factor axis. Clin Cancer Res 9:2734-43

Ngo, Tung H; Barnard, R James; Leung, Pak-Shan et al. (2003) Insulin-like growth factor I (IGF-I) and IGF binding protein-1 modulate prostate cancer cell growth and apoptosis: possible mediators for the effects of diet and exercise on cancer cell survival. Endocrinology 144:2319-24

Monzavi, Roshanak; Cohen, Pinchas (2002) IGFs and IGFBPs: role in health and disease. Best Pract Res Clin Endocrinol Metab 16:433-47

Rajah, Roopmathy; Lee, Kuk-Wha; Cohen, Pinchas (2002) Insulin-like growth factor binding protein-3 mediates tumor necrosis factor-alpha-induced apoptosis: role of Bcl-2 phosphorylation. Cell Growth Differ 13:163-71

Grimberg, Adda; Liu, Bingrong; Bannerman, Peter et al. (2002) IGFBP-3 mediates p53-induced apoptosis during serum starvation. Int J Oncol 21:327-35