Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK047890-02
Application #
2147812
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1995-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Pharmacology
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Mock, Donald M (2017) Biotin: From Nutrition to Therapeutics. J Nutr 147:1487-1492
Luo, X; Popov, S; Bera, A K et al. (2001) RGS proteins provide biochemical control of agonist-evoked [Ca2+]i oscillations. Mol Cell 7:651-60
Davignon, I; Catalina, M D; Smith, D et al. (2000) Normal hematopoiesis and inflammatory responses despite discrete signaling defects in Galpha15 knockout mice. Mol Cell Biol 20:797-804
Popov, S G; Krishna, U M; Falck, J R et al. (2000) Ca2+/Calmodulin reverses phosphatidylinositol 3,4, 5-trisphosphate-dependent inhibition of regulators of G protein-signaling GTPase-activating protein activity. J Biol Chem 275:18962-8
Luo, X; Zeng, W; Xu, X et al. (1999) Alternate coupling of receptors to Gs and Gi in pancreatic and submandibular gland cells. J Biol Chem 274:17684-90
Gasa, R; Trinh, K Y; Yu, K et al. (1999) Overexpression of G11alpha and isoforms of phospholipase C in islet beta-cells reveals a lack of correlation between inositol phosphate accumulation and insulin secretion. Diabetes 48:1035-44
Offermanns, S; Zhao, L P; Gohla, A et al. (1998) Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice. EMBO J 17:4304-12
Popov, S; Yu, K; Kozasa, T et al. (1997) The regulators of G protein signaling (RGS) domains of RGS4, RGS10, and GAIP retain GTPase activating protein activity in vitro. Proc Natl Acad Sci U S A 94:7216-20
Sarwal, M M; Sontag, J M; Hoang, L et al. (1996) G protein alpha subunit multigene family in the Japanese puffer fish Fugu rubripes: PCR from a compact vertebrate genome. Genome Res 6:1207-15
Berman, D M; Wilkie, T M; Gilman, A G (1996) GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits. Cell 86:445-52