Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK048996-03
Application #
2149532
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1994-09-30
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Day, Brian J; van Heeckeren, Anna M; Min, Elysia et al. (2004) Role for cystic fibrosis transmembrane conductance regulator protein in a glutathione response to bronchopulmonary pseudomonas infection. Infect Immun 72:2045-51
Tosi, M F; van Heeckeren, A; Ferkol, T W et al. (2004) Effect of Pseudomonas-induced chronic lung inflammation on specific cytotoxic T-cell responses to adenoviral vectors in mice. Gene Ther 11:1427-33
Ferkol, Thomas; Cohn, Leah A; Phillips, Thomas E et al. (2003) Targeted delivery of antiprotease to the epithelial surface of human tracheal xenografts. Am J Respir Crit Care Med 167:1374-9
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Ferkol, T; Eckman, E; Swaidani, S et al. (2000) Transport of bifunctional proteins across respiratory epithelial cells via the polymeric immunoglobulin receptor. Am J Respir Crit Care Med 161:944-51
Ferkol, T; Mularo, F; Hilliard, J et al. (1998) Transfer of the human Alpha1-antitrypsin gene into pulmonary macrophages in vivo. Am J Respir Cell Mol Biol 18:591-601
Sivaraman, L; Stephens, L C; Markaverich, B M et al. (1998) Hormone-induced refractoriness to mammary carcinogenesis in Wistar-Furth rats. Carcinogenesis 19:1573-81
van Heeckeren, A; Ferkol, T; Tosi, M (1998) Effects of bronchopulmonary inflammation induced by pseudomonas aeruginosa on adenovirus-mediated gene transfer to airway epithelial cells in mice. Gene Ther 5:345-51
Flotte, T R; Ferkol, T W (1997) Genetic therapy. Past, present, and future. Pediatr Clin North Am 44:153-78
Heeckeren, A; Walenga, R; Konstan, M W et al. (1997) Excessive inflammatory response of cystic fibrosis mice to bronchopulmonary infection with Pseudomonas aeruginosa. J Clin Invest 100:2810-5

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