Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK049618-03S1
Application #
2016966
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1994-08-01
Project End
1998-07-31
Budget Start
1996-09-30
Budget End
1997-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Li, X; Mukai, T; Young, D et al. (1998) Transduction of CD34+ cells by a vesicular stomach virus protein G (VSV-G) pseudotyped HIV-1 vector. Stable gene expression in progeny cells, including dendritic cells. J Hum Virol 1:346-52
Gervaix, A; Li, X; Kraus, G et al. (1997) Multigene antiviral vectors inhibit diverse human immunodeficiency virus type 1 clades. J Virol 71:3048-53
Gervaix, A; Schwarz, L; Law, P et al. (1997) Gene therapy targeting peripheral blood CD34+ hematopoietic stem cells of HIV-infected individuals. Hum Gene Ther 8:2229-38
Rosenzweig, M; Marks, D F; Hempel, D et al. (1997) Intracellular immunization of rhesus CD34+ hematopoietic progenitor cells with a hairpin ribozyme protects T cells and macrophages from simian immunodeficiency virus infection. Blood 90:4822-31
Gervaix, A; West, D; Leoni, L M et al. (1997) A new reporter cell line to monitor HIV infection and drug susceptibility in vitro. Proc Natl Acad Sci U S A 94:4653-8
Heusch, M; Kraus, G; Johnson, P et al. (1996) Intracellular immunization against SIVmac utilizing a hairpin ribozyme. Virology 216:241-4
Yamada, O; Kraus, G; Luznik, L et al. (1996) A chimeric human immunodeficiency virus type 1 (HIV-1) minimal Rev response element-ribozyme molecule exhibits dual antiviral function and inhibits cell-cell transmission of HIV-1. J Virol 70:1596-601
Yu, M; Leavitt, M C; Maruyama, M et al. (1995) Intracellular immunization of human fetal cord blood stem/progenitor cells with a ribozyme against human immunodeficiency virus type 1. Proc Natl Acad Sci U S A 92:699-703