Stretch Activated Signaling in Bladder Smooth Muscle

Tuttle, Jeremy B.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 1R01DK050164-01A1
• Application #: 2151185
• Study Section: Surgery, Anesthesiology and Trauma Study Section (SAT)
• Project Start: 1996-05-01
• Project End: 1999-04-30
• Budget Start: 1996-05-01
• Budget End: 1997-04-30
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: University of Virginia
• Department: Urology
• Type: Schools of Medicine
• DUNS #: 001910777
• City: Charlottesville
• State: VA
• Country: United States
• Zip Code: 22904

Publications

Clemow, D B; Steers, W D; Tuttle, J B (2000) Stretch-activated signaling of nerve growth factor secretion in bladder and vascular smooth muscle cells from hypertensive and hyperactive rats. J Cell Physiol 183:289-300

Sherer, T B; Clemow, D B; Tuttle, J B (2000) Calcium homeostasis and nerve growth factor secretion from vascular and bladder smooth muscle cells. Cell Tissue Res 299:201-11

Steers, W D; Clemow, D B; Persson, K et al. (1999) Observations from the spontaneously hypertensive rat. Insight into NGF regulation and noradrenergic hyper-innervation in the lower urinary tract. Adv Exp Med Biol 462:283-92;discussion 311-20

Sherer, T B; Neff, P S; Tuttle, J B (1998) Increased nerve growth factor mRNA stability may underlie elevated nerve growth factor secretion from hypertensive vascular smooth muscle cells. Brain Res Mol Brain Res 62:167-74

Clemow, D B; Spitsbergen, J M; McCarty, R et al. (1998) Arterial nerve growth factor (NGF) mRNA, protein, and vascular smooth muscle cell NGF secretion in hypertensive and hyperactive rats. Exp Cell Res 244:196-205

Clemow, D B; McCarty, R; Steers, W D et al. (1997) Efferent and afferent neuronal hypertrophy associated with micturition pathways in spontaneously hypertensive rats. Neurourol Urodyn 16:293-303