Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK050647-02
Application #
6138024
Study Section
Metabolism Study Section (MET)
Program Officer
Yanovski, Susan Z
Project Start
1999-01-15
Project End
2002-12-31
Budget Start
2000-01-01
Budget End
2000-12-31
Support Year
2
Fiscal Year
2000
Total Cost
$244,983
Indirect Cost
Name
Tufts University
Department
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Rogers, Nicole H; Perfield 2nd, James W; Strissel, Katherine J et al. (2010) Loss of ovarian function in mice results in abrogated skeletal muscle PPARdelta and FoxO1-mediated gene expression. Biochem Biophys Res Commun 392:1-3
Miyoshi, Hideaki; Souza, Sandra C; Endo, Mikiko et al. (2010) Perilipin overexpression in mice protects against diet-induced obesity. J Lipid Res 51:975-82
Rogers, Nicole H; Perfield 2nd, James W; Strissel, Katherine J et al. (2009) Reduced energy expenditure and increased inflammation are early events in the development of ovariectomy-induced obesity. Endocrinology 150:2161-8
Rogers, Nicole H; Witczak, Carol A; Hirshman, Michael F et al. (2009) Estradiol stimulates Akt, AMP-activated protein kinase (AMPK) and TBC1D1/4, but not glucose uptake in rat soleus. Biochem Biophys Res Commun 382:646-50
Danilova, Olga V; Tai, Albert K; Mele, Deanna A et al. (2009) Neurogenin 3-specific dipeptidyl peptidase-2 deficiency causes impaired glucose tolerance, insulin resistance, and visceral obesity. Endocrinology 150:5240-8
Shen, Wen-Jun; Patel, Shailja; Miyoshi, Hideaki et al. (2009) Functional interaction of hormone-sensitive lipase and perilipin in lipolysis. J Lipid Res 50:2306-13
D'Eon, Tara M; Rogers, Nicole H; Stancheva, Zlatina S et al. (2008) Estradiol and the estradiol metabolite, 2-hydroxyestradiol, activate AMP-activated protein kinase in C2C12 myotubes. Obesity (Silver Spring) 16:1284-8
Miyoshi, Hideaki; Perfield 2nd, James W; Obin, Martin S et al. (2008) Adipose triglyceride lipase regulates basal lipolysis and lipid droplet size in adipocytes. J Cell Biochem 105:1430-6
Gauthier, Marie-Soleil; Miyoshi, Hideaki; Souza, Sandra C et al. (2008) AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance. J Biol Chem 283:16514-24
Strissel, Katherine J; Stancheva, Zlatina; Miyoshi, Hideaki et al. (2007) Adipocyte death, adipose tissue remodeling, and obesity complications. Diabetes 56:2910-8

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