Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK050669-02
Application #
2151711
Study Section
Special Emphasis Panel (SRC (24))
Project Start
1995-06-01
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Medical Br Galveston
Department
Pediatrics
Type
Schools of Medicine
DUNS #
041367053
City
Galveston
State
TX
Country
United States
Zip Code
77555
Beswick, Ellen J; Pinchuk, Iryna V; Earley, Rachel B et al. (2011) Role of gastric epithelial cell-derived transforming growth factor beta in reduced CD4+ T cell proliferation and development of regulatory T cells during Helicobacter pylori infection. Infect Immun 79:2737-45
Beswick, Ellen J; Reyes, Victor E (2009) CD74 in antigen presentation, inflammation, and cancers of the gastrointestinal tract. World J Gastroenterol 15:2855-61
Beswick, Ellen J; Reyes, Victor E (2008) Macrophage migration inhibitory factor and interleukin-8 produced by gastric epithelial cells during Helicobacter pylori exposure induce expression and activation of the epidermal growth factor receptor. Infect Immun 76:3233-40
Lu, Hong; Wu, Jeng Yih; Beswick, Ellen J et al. (2007) Functional and intracellular signaling differences associated with the Helicobacter pylori AlpAB adhesin from Western and East Asian strains. J Biol Chem 282:6242-54
Minohara, Yutaka; Boyd, David K; Hawkins, Hal K et al. (2007) The effect of the cag pathogenicity island on binding of Helicobacter pylori to gastric epithelial cells and the subsequent induction of apoptosis. Helicobacter 12:583-90
Beswick, Ellen J; Pinchuk, Irina V; Das, Soumita et al. (2007) Expression of the programmed death ligand 1, B7-H1, on gastric epithelial cells after Helicobacter pylori exposure promotes development of CD4+ CD25+ FoxP3+ regulatory T cells. Infect Immun 75:4334-41
Ding, Song-Ze; Minohara, Yutaka; Fan, Xue Jun et al. (2007) Helicobacter pylori infection induces oxidative stress and programmed cell death in human gastric epithelial cells. Infect Immun 75:4030-9
Bland, David A; Suarez, Giovanni; Beswick, Ellen J et al. (2006) H pylori receptor MHC class II contributes to the dynamic gastric epithelial apoptotic response. World J Gastroenterol 12:4689-93
Suarez, Giovanni; Reyes, Victor E; Beswick, Ellen J (2006) Immune response to H. pylori. World J Gastroenterol 12:5593-8
Beswick, Ellen J; Pinchuk, Irina V; Minch, Kyle et al. (2006) The Helicobacter pylori urease B subunit binds to CD74 on gastric epithelial cells and induces NF-kappaB activation and interleukin-8 production. Infect Immun 74:1148-55

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