Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK051183-02S1
Application #
2632812
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1996-06-01
Project End
1999-05-31
Budget Start
1997-06-30
Budget End
1998-05-31
Support Year
2
Fiscal Year
1997
Total Cost
Indirect Cost

  Institution

Name
University of Pittsburgh
Department
Pharmacology
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213

  Publications

Andresen, Bradley T; Romero, Guillermo G; Jackson, Edwin K (2004) AT2 receptors attenuate AT1 receptor-induced phospholipase D activation in vascular smooth muscle cells. J Pharmacol Exp Ther 309:425-31
Andresen, Bradley T; Linnoila, Jenny J; Jackson, Edwin K et al. (2003) Role of EGFR transactivation in angiotensin II signaling to extracellular regulated kinase in preglomerular smooth muscle cells. Hypertension 41:781-6
Li, Hai-Sheng; Shome, Kuntala; Rojas, Raul et al. (2003) The guanine nucleotide exchange factor ARNO mediates the activation of ARF and phospholipase D by insulin. BMC Cell Biol 4:13
Pathre, Purnima; Shome, Kuntala; Blumental-Perry, Anna et al. (2003) Activation of phospholipase D by the small GTPase Sar1p is required to support COPII assembly and ER export. EMBO J 22:4059-69
Rizzo, M A; Kraft, C A; Watkins, S C et al. (2001) Agonist-dependent traffic of raft-associated Ras and Raf-1 is required for activation of the mitogen-activated protein kinase cascade. J Biol Chem 276:34928-33
Andresen, B T; Jackson, E K; Romero, G G (2001) Angiotensin II signaling to phospholipase D in renal microvascular smooth muscle cells in SHR. Hypertension 37:635-9
Shome, K; Rizzo, M A; Vasudevan, C et al. (2000) The activation of phospholipase D by endothelin-1, angiotensin II, and platelet-derived growth factor in vascular smooth muscle A10 cells is mediated by small G proteins of the ADP-ribosylation factor family. Endocrinology 141:2200-8
Rizzo, M A; Shome, K; Vasudevan, C et al. (1999) Phospholipase D and its product, phosphatidic acid, mediate agonist-dependent raf-1 translocation to the plasma membrane and the activation of the mitogen-activated protein kinase pathway. J Biol Chem 274:1131-9
Rizzo, M A; Romero, G (1998) The role of G proteins in insulin signalling. J Basic Clin Physiol Pharmacol 9:167-95
Vasudevan, C; Han, W; Tan, Y et al. (1998) The distribution and translocation of the G protein ADP-ribosylation factor 1 in live cells is determined by its GTPase activity. J Cell Sci 111 ( Pt 9):1277-85

Showing the most recent 10 out of 12 publications