Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK051417-02
Application #
2152483
Study Section
Special Emphasis Panel (ZHL1-CSR-Q (S2))
Project Start
1995-09-30
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
075524595
City
Seattle
State
WA
Country
United States
Zip Code
98109
Kahl, Christoph; Mielcarek, Marco; Iwata, Mineo et al. (2004) Radiation dose determines the degree of myeloid engraftment after nonmyeloablative stem cell transplantation. Biol Blood Marrow Transplant 10:826-33
Junghanss, Christian; Takatu, Alessandra; Little, Marie-Terese et al. (2003) Adoptive immunotherapy against kidney targets in dog-leukocyte antigen-identical mixed hematopoietic canine chimeras. Transplantation 75:268-74
Kuhr, Christian S; Allen, Margaret D; Junghanss, Christian et al. (2002) Tolerance to vascularized kidney grafts in canine mixed hematopoietic chimeras. Transplantation 73:1487-92
Zaucha, J M; Gooley, T; Bensinger, W I et al. (2001) CD34 cell dose in granulocyte colony-stimulating factor-mobilized peripheral blood mononuclear cell grafts affects engraftment kinetics and development of extensive chronic graft-versus-host disease after human leukocyte antigen-identical sibling transpla Blood 98:3221-7
Graf, L; Heimfeld, S; Torok-Storb, B (2001) Comparison of gene expression in CD34+ cells from bone marrow and G-CSF-mobilized peripheral blood by high-density oligonucleotide array analysis. Biol Blood Marrow Transplant 7:486-94
Zaucha, J M; Zellmer, E; Georges, G et al. (2001) G-CSF-mobilized peripheral blood mononuclear cells added to marrow facilitates engraftment in nonmyeloablated canine recipients: CD3 cells are required. Biol Blood Marrow Transplant 7:613-9
Iwata, M; Vieira, J; Byrne, M et al. (1999) Interleukin-1 (IL-1) inhibits growth of cytomegalovirus in human marrow stromal cells: inhibition is reversed upon removal of IL-1. Blood 94:572-8
Torok-Storb, B; Iwata, M; Graf, L et al. (1999) Dissecting the marrow microenvironment. Ann N Y Acad Sci 872:164-70
Tanaka, J; Mielcarek, M; Torok-Storb, B (1998) Impaired induction of the CD28-responsive complex in granulocyte colony-stimulating factor mobilized CD4 T cells. Blood 91:347-52
Mielcarek, M; Graf, L; Johnson, G et al. (1998) Production of interleukin-10 by granulocyte colony-stimulating factor-mobilized blood products: a mechanism for monocyte-mediated suppression of T-cell proliferation. Blood 92:215-22

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