Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK052501-06S2
Application #
6880695
Study Section
Nutrition Study Section (NTN)
Program Officer
May, Michael K
Project Start
1997-05-01
Project End
2007-04-30
Budget Start
2003-05-01
Budget End
2004-04-30
Support Year
6
Fiscal Year
2004
Total Cost
$14,712
Indirect Cost
Name
University of Illinois Urbana-Champaign
Department
Nutrition
Type
Schools of Earth Sciences/Natur
DUNS #
041544081
City
Champaign
State
IL
Country
United States
Zip Code
61820
Ganu, Radhika S; Ishida, Yasuko; Koutmos, Markos et al. (2015) Evolutionary Analyses and Natural Selection of Betaine-Homocysteine S-Methyltransferase (BHMT) and BHMT2 Genes. PLoS One 10:e0134084
Ganu, Radhika; Garrow, Timothy; Koutmos, Markos et al. (2013) Splicing variants of the porcine betaine-homocysteine S-methyltransferase gene: implications for mammalian metabolism. Gene 529:228-37
Ganu, Radhika S; Garrow, Timothy A; Sodhi, Monika et al. (2011) Molecular characterization and analysis of the porcine betaine homocysteine methyltransferase and betaine homocysteine methyltransferase-2 genes. Gene 473:133-8
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Liu, Hong-Hsing; Lu, Peng; Guo, Yingying et al. (2010) An integrative genomic analysis identifies Bhmt2 as a diet-dependent genetic factor protecting against acetaminophen-induced liver toxicity. Genome Res 20:28-35
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Vanek, Václav; Budesínský, Milos; Kabeleová, Petra et al. (2009) Structure-activity study of new inhibitors of human betaine-homocysteine S-methyltransferase. J Med Chem 52:3652-65
Castro, Carmen; Millian, Norman S; Garrow, Timothy A (2008) Liver betaine-homocysteine S-methyltransferase activity undergoes a redox switch at the active site zinc. Arch Biochem Biophys 472:26-33