Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK054774-06
Application #
6695298
Study Section
Alcohol and Toxicology Subcommittee 4 (ALTX)
Program Officer
Margolis, Ronald N
Project Start
1999-03-15
Project End
2006-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
6
Fiscal Year
2004
Total Cost
$256,375
Indirect Cost

  Institution

Name
University of Louisville
Department
Biochemistry
Type
Schools of Medicine
DUNS #
057588857
City
Louisville
State
KY
Country
United States
Zip Code
40292

  Publications

Guardiola, John J; Beier, Juliane I; Falkner, K Cameron et al. (2016) Occupational exposures at a polyvinyl chloride production facility are associated with significant changes to the plasma metabolome. Toxicol Appl Pharmacol 313:47-56
Miller, Kristy K Michael; Al-Rayyan, Numan; Ivanova, Margarita M et al. (2013) DHEA metabolites activate estrogen receptors alpha and beta. Steroids 78:15-25
Robinzon, B; Prough, R A (2009) A novel NADP(+)-dependent dehydrogenase activity for 7alpha/beta- and 11beta-hydroxysteroids in human liver nuclei: A third 11beta-hydroxysteroid dehydrogenase. Arch Biochem Biophys 486:170-6
Falkner, K C; Ritter, J K; Prough, R A (2008) Regulation of the rat UGT1A6 by glucocorticoids involves a cryptic glucocorticoid response element. Drug Metab Dispos 36:409-17
Tamasi, Viola; Miller, Kristy K Michael; Ripp, Sharon L et al. (2008) Modulation of receptor phosphorylation contributes to activation of peroxisome proliferator activated receptor alpha by dehydroepiandrosterone and other peroxisome proliferators. Mol Pharmacol 73:968-76
Kohalmy, Krisztina; Tamasi, Viola; Kobori, Laszlo et al. (2007) Dehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptor. Drug Metab Dispos 35:1495-501
Falkner, K Cameron; Prough, Russell A (2007) Regulation of the rat glutathione S-transferase A2 gene by glucocorticoids: crosstalk through C/EBPs. Drug Metab Rev 39:401-18
Bertrand, C A; Laboisse, C; Hopfer, U et al. (2006) Methods for detecting internalized, FM 1-43 stained particles in epithelial cells and monolayers. Biophys J 91:3872-83
Webb, Stephanie J; Geoghegan, Thomas E; Prough, Russell A et al. (2006) The biological actions of dehydroepiandrosterone involves multiple receptors. Drug Metab Rev 38:89-116
Robinzon, Boaz; Prough, Russell A (2005) Interactions between dehydroepiandrosterone and glucocorticoid metabolism in pig kidney: nuclear and microsomal 11beta-hydroxysteroid dehydrogenases. Arch Biochem Biophys 442:33-40

Showing the most recent 10 out of 22 publications