Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK059508-01A1S1
Application #
6704591
Study Section
General Medicine A Subcommittee 2 (GMA)
Program Officer
Serrano, Jose
Project Start
2002-05-01
Project End
2007-04-30
Budget Start
2002-05-01
Budget End
2003-04-30
Support Year
1
Fiscal Year
2003
Total Cost
$57,612
Indirect Cost
Name
University of California Los Angeles
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Lugea, Aurelia; Waldron, Richard T; Pandol, Stephen J (2015) Pancreatic adaptive responses in alcohol abuse: Role of the unfolded protein response. Pancreatology 15:S1-5
Mukherjee, R; Criddle, D N; Gukovskaya, A et al. (2008) Mitochondrial injury in pancreatitis. Cell Calcium 44:14-23
Fischer, L; Gukovskaya, A S; Penninger, J M et al. (2007) Phosphatidylinositol 3-kinase facilitates bile acid-induced Ca(2+) responses in pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol 292:G875-86
Ito, Yoshiya; Lugea, Aurelia; Pandol, Stephen J et al. (2007) Substance P mediates cerulein-induced pancreatic microcirculatory dysfunction in mice. Pancreas 34:138-43
Satoh, Akihiko; Gukovskaya, Anna S; Reeve Jr, Joseph R et al. (2006) Ethanol sensitizes NF-kappaB activation in pancreatic acinar cells through effects on protein kinase C-epsilon. Am J Physiol Gastrointest Liver Physiol 291:G432-8
Wang, Yan-Ling; Hu, Richard; Lugea, Aurelia et al. (2006) Ethanol feeding alters death signaling in the pancreas. Pancreas 32:351-9
Satoh, Akihiko; Gukovskaya, Anna S; Edderkaoui, Mouad et al. (2005) Tumor necrosis factor-alpha mediates pancreatitis responses in acinar cells via protein kinase C and proline-rich tyrosine kinase 2. Gastroenterology 129:639-51
Gukovskaya, Anna S; Hosseini, Saeed; Satoh, Akihiko et al. (2004) Ethanol differentially regulates NF-kappaB activation in pancreatic acinar cells through calcium and protein kinase C pathways. Am J Physiol Gastrointest Liver Physiol 286:G204-13
Satoh, Akihiko; Gukovskaya, Anna S; Nieto, Jose M et al. (2004) PKC-delta and -epsilon regulate NF-kappaB activation induced by cholecystokinin and TNF-alpha in pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol 287:G582-91
Gukovskaya, Anna S; Pandol, Stephen J (2004) Cell death pathways in pancreatitis and pancreatic cancer. Pancreatology 4:567-86

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