Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK059580-03
Application #
6517910
Study Section
General Medicine A Subcommittee 2 (GMA)
Program Officer
Serrano, Jose
Project Start
2000-09-30
Project End
2005-06-30
Budget Start
2002-07-01
Budget End
2003-06-30
Support Year
3
Fiscal Year
2002
Total Cost
$221,235
Indirect Cost
Name
Northwestern University at Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Liu, Xiaoying; Guo, Grace L; Kong, Bo et al. (2018) Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice. Hepatology 68:304-316
Koppe, Sean W P; Elias, Marc; Moseley, Richard H et al. (2009) Trans fat feeding results in higher serum alanine aminotransferase and increased insulin resistance compared with a standard murine high-fat diet. Am J Physiol Gastrointest Liver Physiol 297:G378-84
Johnson, Laura E; Elias, Marc S; Bolick, David T et al. (2008) The G protein-coupled receptor G2A: involvement in hepatic lipid metabolism and gallstone formation in mice. Hepatology 48:1138-48
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Rinella, Mary E; Elias, Marc S; Smolak, Robin R et al. (2008) Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet. J Lipid Res 49:1068-76
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Henkel, Anne; Wei, Zhixin; Cohen, David E et al. (2005) Mice overexpressing hepatic Abcb11 rapidly develop cholesterol gallstones. Mamm Genome 16:903-8
Sundaram, Shikha S; Whitington, Peter F; Green, Richard M (2005) Steatohepatitis develops rapidly in transgenic mice overexpressing Abcb11 and fed a methionine-choline-deficient diet. Am J Physiol Gastrointest Liver Physiol 288:G1321-7
Koppe, Sean W P; Sahai, Atul; Malladi, Padmini et al. (2004) Pentoxifylline attenuates steatohepatitis induced by the methionine choline deficient diet. J Hepatol 41:592-8
Rinella, Mary E; Green, Richard M (2004) The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance. J Hepatol 40:47-51

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