Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK061382-02
Application #
6696321
Study Section
General Medicine A Subcommittee 2 (GMA)
Program Officer
May, Michael K
Project Start
2003-01-15
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$283,328
Indirect Cost

  Institution

Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

San Roman, Adrianna K; Aronson, Boaz E; Krasinski, Stephen D et al. (2015) Transcription factors GATA4 and HNF4A control distinct aspects of intestinal homeostasis in conjunction with transcription factor CDX2. J Biol Chem 290:1850-60
Baffour-Awuah, Nana Yaa; Fleet, Sarah; Montgomery, Robert K et al. (2015) Functional significance of single nucleotide polymorphisms in the lactase gene in diverse US patients and evidence for a novel lactase persistence allele at -13909 in those of European ancestry. J Pediatr Gastroenterol Nutr 60:182-91
Aronson, Boaz E; Stapleton, Kelly A; Krasinski, Stephen D (2014) Role of GATA factors in development, differentiation, and homeostasis of the small intestinal epithelium. Am J Physiol Gastrointest Liver Physiol 306:G474-90
Aronson, B E; Rabello Aronson, S; Berkhout, R P et al. (2014) GATA4 represses an ileal program of gene expression in the proximal small intestine by inhibiting the acetylation of histone H3, lysine 27. Biochim Biophys Acta 1839:1273-82
Aronson, Boaz E; Stapleton, Kelly A; Vissers, Laurens A T M et al. (2014) Spdef deletion rescues the crypt cell proliferation defect in conditional Gata6 null mouse small intestine. BMC Mol Biol 15:3
Beuling, Eva; Aronson, Boaz E; Tran, Luc M D et al. (2012) GATA6 is required for proliferation, migration, secretory cell maturation, and gene expression in the mature mouse colon. Mol Cell Biol 32:3392-402
Muncan, Vanesa; Heijmans, Jarom; Krasinski, Stephen D et al. (2011) Blimp1 regulates the transition of neonatal to adult intestinal epithelium. Nat Commun 2:452
Beuling, Eva; Baffour-Awuah, Nana Yaa A; Stapleton, Kelly A et al. (2011) GATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature mice. Gastroenterology 140:1219-1229.e1-2
Baffour-Awuah, Nana Yaa; Delemarre, Eveline; Fujiwara, Yuko et al. (2011) Characterization of expression in mice of a transgene containing 3.3 kb of the human lactase-phlorizin hydrolase (LPH) 5' flanking sequence. Dig Dis Sci 56:59-69
Beuling, Eva; Kerkhof, Ilona M; Nicksa, Grace A et al. (2010) Conditional Gata4 deletion in mice induces bile acid absorption in the proximal small intestine. Gut 59:888-95

Showing the most recent 10 out of 16 publications