Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK061566-02
Application #
6696347
Study Section
General Medicine A Subcommittee 2 (GMA)
Program Officer
Doo, Edward
Project Start
2003-01-08
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$324,653
Indirect Cost
Name
University of Colorado Denver
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045
Kim, Seong-Jun; Jang, Jae Young; Kim, Eun-Jung et al. (2017) Ginsenoside Rg3 restores hepatitis C virus-induced aberrant mitochondrial dynamics and inhibits virus propagation. Hepatology 66:758-771
Nasimuzzaman, Md; Waris, Gulam; Mikolon, David et al. (2007) Hepatitis C virus stabilizes hypoxia-inducible factor 1alpha and stimulates the synthesis of vascular endothelial growth factor. J Virol 81:10249-57
Waris, Gulam; Felmlee, Daniel Jeffery; Negro, Francesco et al. (2007) Hepatitis C virus induces proteolytic cleavage of sterol regulatory element binding proteins and stimulates their phosphorylation via oxidative stress. J Virol 81:8122-30
Waris, Gulam; Siddiqui, Aleem (2005) Hepatitis C virus stimulates the expression of cyclooxygenase-2 via oxidative stress: role of prostaglandin E2 in RNA replication. J Virol 79:9725-34
Tardif, Keith D; Waris, Gulam; Siddiqui, Aleem (2005) Hepatitis C virus, ER stress, and oxidative stress. Trends Microbiol 13:159-63
Waris, Gulam; Turkson, James; Hassanein, Tarek et al. (2005) Hepatitis C virus (HCV) constitutively activates STAT-3 via oxidative stress: role of STAT-3 in HCV replication. J Virol 79:1569-80
Domitrovich, Angela M; Diebel, Kevin W; Ali, Naushad et al. (2005) Role of La autoantigen and polypyrimidine tract-binding protein in HCV replication. Virology 335:72-86
Domitrovich, Angela M; Felmlee, Daniel J; Siddiqui, Aleem (2005) Hepatitis C virus nonstructural proteins inhibit apolipoprotein B100 secretion. J Biol Chem 280:39802-8
Tardif, Keith D; Mori, Kazutoshi; Kaufman, Randal J et al. (2004) Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response. J Biol Chem 279:17158-64
Waris, Gulam; Sarker, Shameema; Siddiqui, Aleem (2004) Two-step affinity purification of the hepatitis C virus ribonucleoprotein complex. RNA 10:321-9

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