This project is a feasibility clinical study of the upper extremity Networked Neuroprosthetic (NNP) System to demonstrate efficacy in providing grasp and reach for individuals with cervical level spinal cord injury. The NNP System will electrically stimulate paralyzed muscles in a coordinated fashion to provide grasp and release, forearm pronation, elbow extension, and shoulder/trunk stabilization. The stimulated patterns will be controlled by each subject through activation of their voluntary musculature, as recorded through implanted myoelectric recording electrodes. Subject performance will be assessed through measures of impairment, activities, and participation, with a focus on the ability to perform activities of daily living more independently and on the rate of daily home use. We hypothesize that daily usage will be improved due to the fully implantable nature of the NNP System and that every subject will improve in their functional ability, regardless of their startin function level, due to the modular and customizable nature of the NNP System.
This project is designed to develop and evaluate an advanced, fully-implantable hand neuroprosthesis for individuals with spinal cord injury. The study is relevant to individuals with cervical level spinal cord injury because it provides them with the ability to use their hand and arm more independently.
| Memberg, William D; Stage, Thomas G; Kirsch, Robert F (2014) A fully implanted intramuscular bipolar myoelectric signal recording electrode. Neuromodulation 17:794-9; discussion 799 |
| Peckham, P Hunter; Kilgore, Kevin L (2013) Challenges and opportunities in restoring function after paralysis. IEEE Trans Biomed Eng 60:602-9 |
| Shan, Xi; Payer, Joe H; Wainright, Jesse S et al. (2011) A Micro-fabricated Hydrogen Storage Module with Sub-atmospheric Activation and Durability in Air Exposure. J Power Sources 196:827-834 |
| Ha, Hung; Payer, Joe (2011) The Effect of Silver Chloride Formation on the Kinetics of Silver Dissolution in Chloride Solution. Electrochim Acta 56:2781-2791 |
| Shan, Xi; Payer, Joe H; Wainright, Jesse S et al. (2011) Demonstration of a micro-fabricated hydrogen storage module for micro-power systems. J Power Sources 196:820-826 |
| Ackermann Jr, D Michael; Smith, Brian; Wang, Xiao-Feng et al. (2008) Designing the optical interface of a transcutaneous optical telemetry link. IEEE Trans Biomed Eng 55:1365-73 |
| Lewandowski, John J; Varadarajan, Ravikumar; Smith, Brian et al. (2008) Tension and fatigue behavior of 316LVM 1x7 multi-strand cables used as implantable electrodes. Mater Sci Eng A Struct Mater 486:447-454 |
| Ackermann, D Michael; Smith, Brian; Kilgore, Kevin L et al. (2006) Design of a high speed transcutaneous optical telemetry link. Conf Proc IEEE Eng Med Biol Soc 1:2932-5 |
