Novel Software Tools for Rational Design and Assessment of MR coils The goal of this project is to develop a comprehensive software package for the design and evaluation of radiofrequency (RF) coils for applications in magnetic resonance imaging (MRI). By means of an intuitive graphical user interface, RF engineers will be able to design highly performing receive and transmit coil arrays, tailoring the shape of the individual elements to the specific imaging task and optimally arranging them around the object of interest, thanks to accurate predictions of coil performance. We will also develop standardized evaluation protocols to quantitatively assess coils against well-defined theoretical performance limits, which are calculated by applying electrodynamics principles and provide an absolute reference, independent on any particular coil geometry. We will integrate various software tools into a modular and flexible software architecture, which will enable other researchers to add extensions and develop stand-alone applications. We will validate the accuracy of the simulation tools and evaluate the software utility through a network of beta testers. In addition to coil design, our comprehensive package will enable to test novel pulse sequences and image reconstruction algorithms, making rigorous development of new ideas accessible to the scientific community, including those with no access to MRI systems. The final software, which will be publicly distributed through a dedicated website with a maintenance plan beyond the duration of the project, will become an invaluable tool that will positively impact the field of medical imaging, with benefits for the entire community.

Public Health Relevance

This project is aimed to produce a comprehensive software package for the design and evaluation of radiofrequency coils for applications in magnetic resonance imaging. We will develop a graphical interface for optimized coil design based on accurate performance predictions, as well as novel software tools for quantitative assessment of actual coils, using well-defined theoretical limits as absolute references. Our toolkit will be published as open-source with a flexible, expandable software architecture and it is expected to positively impact the field of medical imaging.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Research Project (R01)
Project #
1R01EB024536-01
Application #
9364167
Study Section
Biomedical Imaging Technology Study Section (BMIT)
Program Officer
Wang, Shumin
Project Start
2017-07-01
Project End
2021-04-30
Budget Start
2017-07-01
Budget End
2018-04-30
Support Year
1
Fiscal Year
2017
Total Cost
Indirect Cost
Name
New York University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10010
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