Animal Models of Alcohol-Related Cancers

Sipes, I G.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Environmental Health Sciences (NIEHS)
• Type: Research Project (R01)
• Project #: 3R01ES003438-01S1
• Application #: 3250729
• Study Section: Chemical Pathology Study Section (CPA)
• Project Start: 1984-12-01
• Project End: 1987-01-31
• Budget Start: 1984-12-01
• Budget End: 1985-01-31
• Support Year: 1
• Fiscal Year: 1985

Institution

• Name: University of Arizona
• Type: Schools of Pharmacy
• City: Tucson
• State: AZ
• Country: United States
• Zip Code: 85722

Publications

Mufti, S I (1991) Free radicals generated in ethanol metabolism may be responsible for tumor promoting effects of ethanol. Adv Exp Med Biol 283:777-83

Mufti, S I; Sipes, I G (1991) A reduction in mixed function oxidases and in tumor promoting effects of ethanol in a NDEA-initiated hepatocarcinogenesis model. Adv Exp Med Biol 283:347-52

Mufti, S I; Darban, H R; Watson, R R (1989) Alcohol, cancer, and immunomodulation. Crit Rev Oncol Hematol 9:243-61

Mufti, S I; Becker, G; Sipes, I G (1989) Effect of chronic dietary ethanol consumption on the initiation and promotion of chemically-induced esophageal carcinogenesis in experimental rats. Carcinogenesis 10:303-9

Mufti, S I; Prabhala, R; Moriguchi, S et al. (1988) Functional and numerical alterations induced by ethanol in the cellular immune system. Immunopharmacology 15:85-93

Mufti, S I; Sipes, I G (1988) Differential induction of DNA strand breaks by nitrosamines in the rat liver and esophagus. Cancer Lett 40:203-11

Szebeni, J; Eskelson, C D; Mufti, S I et al. (1986) Inhibition of ethanol induced ethane exhalation by carcinogenic pretreatment of rats 12 months earlier. Life Sci 39:2587-91