Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES003966-08
Application #
2153496
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1986-05-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Oregon State University
Department
Biochemistry
Type
Schools of Earth Sciences/Natur
DUNS #
053599908
City
Corvallis
State
OR
Country
United States
Zip Code
97339

  Publications

Marshall, Nikki B; Kerkvliet, Nancy I (2010) Dioxin and immune regulation: emerging role of aryl hydrocarbon receptor in the generation of regulatory T cells. Ann N Y Acad Sci 1183:25-37
Vorderstrasse, Beth A; Dearstyne, Erica A; Kerkvliet, Nancy I (2003) Influence of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the antigen-presenting activity of dendritic cells. Toxicol Sci 72:103-12
Shepherd, D M; Steppan, L B; Hedstrom, O R et al. (2001) Anti-CD40 Treatment of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-exposed C57Bl/6 mice induces activation of antigen presenting cells yet fails to overcome TCDD-induced suppression of allograft immunity. Toxicol Appl Pharmacol 170:10-22
Vorderstrasse, B A; Kerkvliet, N I (2001) 2,3,7,8-Tetrachlorodibenzo-p-dioxin affects the number and function of murine splenic dendritic cells and their expression of accessory molecules. Toxicol Appl Pharmacol 171:117-25
Shepherd, D M; Dearstyne, E A; Kerkvliet, N I (2000) The effects of TCDD on the activation of ovalbumin (OVA)-specific DO11.10 transgenic CD4(+) T cells in adoptively transferred mice. Toxicol Sci 56:340-50
Prell, R A; Dearstyne, E; Steppan, L G et al. (2000) CTL hyporesponsiveness induced by 2,3,7, 8-tetrachlorodibenzo-p-dioxin: role of cytokines and apoptosis. Toxicol Appl Pharmacol 166:214-21
Shepherd, D M; Kerkvliet, N I (1999) Disruption of CD154:CD40 blocks generation of allograft immunity without affecting APC activation. J Immunol 163:2470-7
Kerkvliet, N I; Baecher-Steppan, L; Shepherd, D M et al. (1996) Inhibition of TC-1 cytokine production, effector cytotoxic T lymphocyte development and alloantibody production by 2,3,7,8-tetrachlorodibenzo-p-dioxin. J Immunol 157:2310-9
Moos, A B; Kerkvliet, N I (1995) Inhibition of tumor necrosis factor activity fails to restore 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced suppression of the antibody response to sheep red blood cells. Toxicol Lett 81:175-81
DeKrey, G K; Kerkvliet, N I (1995) Effects of exogenous corticosterone treatment on alloantigen-specific cytotoxic T lymphocyte activity in mice. J Pharmacol Exp Ther 273:823-9

Showing the most recent 10 out of 19 publications