Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES006499-04
Application #
2155348
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1993-09-01
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Vermont & St Agric College
Department
Pathology
Type
Schools of Medicine
DUNS #
066811191
City
Burlington
State
VT
Country
United States
Zip Code
05405

  Publications

Shukla, A; Timblin, C; BeruBe, K et al. (2000) Inhaled particulate matter causes expression of nuclear factor (NF)-kappaB-related genes and oxidant-dependent NF-kappaB activation in vitro. Am J Respir Cell Mol Biol 23:182-7
Jung, M; Davis, W P; Taatjes, D J et al. (2000) Asbestos and cigarette smoke cause increased DNA strand breaks and necrosis in bronchiolar epithelial cells in vivo. Free Radic Biol Med 28:1295-9
Robledo, R; Mossman, B (1999) Cellular and molecular mechanisms of asbestos-induced fibrosis. J Cell Physiol 180:158-66
Janssen-Heininger, Y M; Macara, I; Mossman, B T (1999) Cooperativity between oxidants and tumor necrosis factor in the activation of nuclear factor (NF)-kappaB: requirement of Ras/mitogen-activated protein kinases in the activation of NF-kappaB by oxidants. Am J Respir Cell Mol Biol 20:942-52
Zanella, C L; Timblin, C R; Cummins, A et al. (1999) Asbestos-induced phosphorylation of epidermal growth factor receptor is linked to c-fos and apoptosis. Am J Physiol 277:L684-93
Timblin, C R; Guthrie, G D; Janssen, Y W et al. (1998) Patterns of c-fos and c-jun proto-oncogene expression, apoptosis, and proliferation in rat pleural mesothelial cells exposed to erionite or asbestos fibers. Toxicol Appl Pharmacol 151:88-97
Janssen, Y M; Driscoll, K E; Timblin, C R et al. (1998) Modulation of mitochondrial gene expression in pulmonary epithelial cells exposed to oxidants. Environ Health Perspect 106 Suppl 5:1191-5
Mossman, B T; Churg, A (1998) Mechanisms in the pathogenesis of asbestosis and silicosis. Am J Respir Crit Care Med 157:1666-80
Timblin, C R; Janssen, Y M; Goldberg, J L et al. (1998) GRP78, HSP72/73, and cJun stress protein levels in lung epithelial cells exposed to asbestos, cadmium, or H2O2. Free Radic Biol Med 24:632-42
Fung, H; Kow, Y W; Van Houten, B et al. (1998) Asbestos increases mammalian AP-endonuclease gene expression, protein levels, and enzyme activity in mesothelial cells. Cancer Res 58:189-94

Showing the most recent 10 out of 22 publications