Asbestos Induced Oxidative DNA Damage and Repair

Van Houten, Bennett

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Environmental Health Sciences (NIEHS)
• Type: Research Project (R01)
• Project #: 5R01ES007038-03
• Application #: 2156074
• Study Section: Chemical Pathology Study Section (CPA)
• Project Start: 1994-02-21
• Project End: 1999-01-31
• Budget Start: 1996-02-01
• Budget End: 1997-01-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of Texas Medical Br Galveston
• Type: Organized Research Units
• DUNS #: 041367053
• City: Galveston
• State: TX
• Country: United States
• Zip Code: 77555

Publications

Van Houten, B; Cheng, S; Chen, Y (2000) Measuring gene-specific nucleotide excision repair in human cells using quantitative amplification of long targets from nanogram quantities of DNA. Mutat Res 460:81-94

Sawyer, D E; Van Houten, B (1999) Repair of DNA damage in mitochondria. Mutat Res 434:161-76

Pache, J C; Janssen, Y M; Walsh, E S et al. (1998) Increased epidermal growth factor-receptor protein in a human mesothelial cell line in response to long asbestos fibers. Am J Pathol 152:333-40

Jimenez, L A; Zanella, C; Fung, H et al. (1997) Role of extracellular signal-regulated protein kinases in apoptosis by asbestos and H2O2. Am J Physiol 273:L1029-35

Salazar, J J; Van Houten, B (1997) Preferential mitochondrial DNA injury caused by glucose oxidase as a steady generator of hydrogen peroxide in human fibroblasts. Mutat Res 385:139-49