|
Govindarajan, Baskaran; Mizesko, Melissa C; Miller, Mark Steven et al. (2003) Tuberous sclerosis-associated neoplasms express activated p42/44 mitogen-activated protein (MAP) kinase, and inhibition of MAP kinase signaling results in decreased in vivo tumor growth. Clin Cancer Res 9:3469-75
|
|
Govindarajan, Baskaran; Klafter, Robert; Miller, Mark Steven et al. (2002) Reactive oxygen-induced carcinogenesis causes hypermethylation of p16(Ink4a) and activation of MAP kinase. Mol Med 8:1-8
|
|
Mizesko, M C; Grewe, C; Grabner, A et al. (2001) Alterations at the Ink4a locus in transplacentally induced murine lung tumors. Cancer Lett 172:59-66
|
|
Gressani, K M; Leone-Kabler, S; O'Sullivan, M G et al. (2000) Prenatal toxicity and lack of carcinogenicity of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) following transplacental exposure. Toxicol Sci 55:407-14
|
|
Miller, M S; Gressani, K M; Leone-Kabler, S et al. (2000) Differential sensitivity to lung tumorigenesis following transplacental exposure of mice to polycyclic hydrocarbons, heterocyclic amines, and lung tumor promoters. Exp Lung Res 26:709-30
|
|
Miller, M S (1999) Tumor suppressor genes in rodent lung carcinogenesis-mutation of p53 does not appear to be an early lesion in lung tumor pathogenesis. Toxicol Appl Pharmacol 156:70-7
|
|
Gressani, K M; Leone-Kabler, S; O'Sullivan, M G et al. (1999) Strain-dependent lung tumor formation in mice transplacentally exposed to 3-methylcholanthrene and post-natally exposed to butylated hydroxytoluene. Carcinogenesis 20:2159-65
|
|
Gressani, K M; Rollins, L A; Leone-Kabler, S et al. (1998) Induction of mutations in Ki-ras and INK4a in liver tumors of mice exposed in utero to 3-methylcholanthrene. Carcinogenesis 19:1045-52
|
